Results 51 to 60 of about 145,948 (305)
More Precious than Gas? An Unexpected discovery in the Northeastern Funerary Area of Noviodunum [PDF]
Peuce, 2023 The paper analyses several archaeological features discovered during an excavation performed on the outskirts of Isaccea, during the summer of 2018, in the easternmost part of the Noviodunum archaeological site.
Radu-Octavian STĂNESCU +5 more
doaj
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Carbon burial characteristics of Hongze Lake in the past 60 years
Shuiwen dizhi gongcheng dizhiLakes are important carbon sinks in terrestrial ecosystems. Currently, most of lake carbon burial research in China only considers organic carbon burial and has neglected inorganic carbon burial, which will lead to an underestimation of the total carbon ...
Jiahao QI, Taibei LIU, Hua ZHAO
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Applied SciencesThe deformation characteristics of the surrounding rock in tunnel groups are considered critical for the design of support structures and the assurance of the long-term safety of deep-buried diversion tunnels. The deformation behavior of surrounding rock
Zhiyun Deng +7 more
doaj +1 more source
Human Skeletal Remains from the Tyson Site (41SY92) [PDF]
, 1994 During the 1993 field season at the Tyson site (41SY92), conducted by the East Texas and Northeast Texas Archaeological societies, two burial features were uncovered.
Dockall, Helen D.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Energy Exploration & Exploitation, 2022 The Bongor Basin is a typical lacustrine passive-rifted basin situated in the West and Central African Rift System (WCARS). It has experienced two phases of tectonic inversion and features a complex process of petroleum generation and accumulation.
Dingsheng Cheng +3 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source