Results 131 to 140 of about 939,140 (300)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Principals’ Transformational Leadership Practices and Quality of Education in Secondary Schools in Kiambu County

, 2021
Nancy W. Kariuki Kihanga, Paul Maku Gichohi, N.J. Kathuri   +2 more
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Key Competencies for Adolescent Well-Being: An Intervention Program in Secondary Education. [PDF]

Eur J Investig Health Psychol Educ
Molina Moreno P, Simón Márquez MDM, Pérez-Fuentes MDC, Molero Jurado MDM.   +3 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

"I Just Get a Different Feeling in This Class": Belonging as Affective Praxis at a Dutch Urban Secondary Education School. [PDF]

J Community Psychol
Çolak FZ, Parra SL, Wansink B.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Social-emotional architecture of adolescent success: a mixed-methods investigation of social-emotional learning pathways in Chinese secondary education. [PDF]

Front Psychol
Qi L, Hong WCH, Xue L, Xu X, Wei W.
europepmc   +1 more source

Cyberbullying and Psychopathological Behaviors in Spanish Secondary Education Students. [PDF]

Healthcare (Basel), 2023
Contreras-Piqueras ÁE, Ruiz-Esteban C, Méndez I.   +2 more
europepmc   +1 more source

MODELING OF THE SYSTEM OF MANAGEMENT OF EDUCATIONAL PROCESS AS A BASIS FOR IMPROVING THE QUALITY OF MATHEMATICAL AND NATURAL EDUCATION IN SECONDARY EDUCATION INSTITUTIONS

, 2020
Yuriy Vasyliovych Kyrychkov
openalex   +1 more source