Results 261 to 270 of about 3,439,590 (350)

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone

open access: yesAdvanced Biology, EarlyView.
In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman   +5 more
wiley   +1 more source

Machine learning predicts upper secondary education dropout as early as the end of primary school. [PDF]

open access: yesSci Rep
Psyridou M   +5 more
europepmc   +1 more source

Influence of a Standard Heat Treatment on the Microstructure and Properties of Inconel X‐750 Produced by Laser Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Ni‐base superalloys produced using additive manufacturing (AM) have a different response to heat treatments when compared to their conventional counterparts. Due to such unpredictability, various alloys with industrial interest are currently overlooked in most prior AM research.
Guilherme Maziero Volpato   +6 more
wiley   +1 more source

Mitigation of Cracks in High‐Performance Nickel‐Based Superalloys in Powder Bed Fusion Laser Beam of Metals Using a Metal Matrix Composite Approach

open access: yesAdvanced Engineering Materials, EarlyView.
High‐performance nickel‐based superalloys are often not processible in additive manufacturing (AM) due to hot cracking. The findings in this manuscript propose an efficient method to mitigate cracking and enhance mechanical properties of these alloys by producing a metal matrix composite, contributing to the material and process perspective of the AM ...
Klaus Büßenschütt   +3 more
wiley   +1 more source

Emotions and music through an innovative project during compulsory secondary education. [PDF]

open access: yesHeliyon
Valero-Esteban JM   +4 more
europepmc   +1 more source

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

open access: yesAdvanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel   +6 more
wiley   +1 more source

Development of competencies in secondary education through the motivational style of autonomy support. [PDF]

open access: yesF1000Res
Llorca-Cano M   +3 more
europepmc   +1 more source

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