Results 121 to 130 of about 1,860,659 (307)

Assessment strategies for cross-curricular programming in secondary education

open access: yes, 2023
The increasing integration of computer science and programming into formal school education is a commendable endeavor that has seen different implementation solutions. Sweden and Norway have opted for a cross-curricular model, incorporating the task of teaching and learning computing into already existing subjects, mainly within STEM modules.
Fuentes-Martinez, Ana   +3 more
openaire   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Towards pedagogies of creative collaboration: guiding secondary school students' music compositions [PDF]

open access: yes, 2014
The pedagogy of creative collaboration in music classrooms is hardly clear from the literature. There are plenty of strategies for setting up composition activities and some useful models for peer and self-assessment.
Odena, Oscar
core  

Watching, assessing, participating. : Globalising political education in Norwegian upper secondary education

open access: yes, 2019
Transnational governance is expanding rapidly. From a political education perspective, an important question is to what extent and how these are included in the political universe that adolescents are being prepared for at school. Of particular interest is social science, which is part of social studies in primary and lower secondary school, before it ...
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Teacher Challenges to Implement Engineering Design in Secondary Technology Education (Third in a Three Part Series) [PDF]

open access: yes, 2009
This descriptive study examined the current status of technology education teacher practices with respect to engineering design. This article is the third article in a three-part series presenting the results of this study.
Kelley, Todd R., Wicklein, Robert C.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Iterative and ipsative assessment integration in secondary mathematics education

open access: yes, 2021
The importance of multiliteracy and personalized, differentiated instruction demands educators to rethink the tools and strategies that they use to assess and communicate student progress. Drawing upon the notions of growth mindset and visible thinking, this project aims to present several non-traditional assessment tools and templates that can be used
openaire   +2 more sources

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