Results 71 to 80 of about 1,860,659 (307)

An Assessment of Secondary Traumatic Stress in Juvenile Justice Education Workers [PDF]

open access: yesJournal of Correctional Health Care, 2011
Given the frequency and violent character of the traumas encountered by juvenile offenders, staff members who regularly interact with juveniles in custody are at risk of developing secondary traumatic stress. Juvenile justice teachers and staff (N = 118) were administered a cross-sectional survey, including the Secondary Traumatic Stress Scale ...
Schnavia, Smith Hatcher   +4 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Système éducatif portugais

open access: yesCarnets, 2016
This communication aimed at presenting the Portuguese education system, its principles and priorities, its structure, its courses, the primary education curriculum and that of secondary education, as well as assessment and certification; analysing the ...
Eulália Alexandre
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Study of Assessment Practices of Secondary School Civic Education Teachers in Kaduna State, Nigeria

open access: yesEducational Process: International Journal
Background/purpose. This study investigated the assessment practices of secondary school civic education teachers in Kaduna State, Nigeria, focusing on the evaluation methods, tools, and strategies used to assess students' understanding and mastery of ...
Asokan Vasudevan   +7 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Relating the Slovenian secondary school English language national examinations to the CEFR: findings and implications

open access: yesLinguistica, 2014
The present paper draws on the report of a five-year project that aligned the Slovenian national exams in English to the Common European Framework of Reference for Languages: Learning, teaching, assessment (CEFR).
Gašper Ilc   +2 more
doaj   +1 more source

Education and Skills: An Assessment of Recent Canadian Experience [PDF]

open access: yes
The skills issue is currently at or near the top of the federal government’s policy agenda, given its importance for harnessing the benefits of technological advances.
Andrew Sharpe   +2 more
core  

Examination of Assessment Practices for Engineering Design Projects in Secondary Education (First in a Three Part Series) [PDF]

open access: yes, 2009
The following descriptive study was designed to determine the national status of secondary technology education curriculum content and assessment practices as they relate to engineering design.
Kelley, Todd R., Wicklein, Robert C.
core   +1 more source

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