RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Technology education teacher development in solomon islands: Enhancing teachers’ perceptions and classroom practices [PDF]
Technology education in the Solomon Islands is in the process of change with the curriculum being developed into a more broad technological literacy approach, comprising of technological knowledge, technological practices, and the nature of technology ...
Jones, Alister +2 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Transition to Teaching: An Alternative Certification Program through Partnership Between a Public School District and a Public University [PDF]
The reauthorization of the Elementary and Secondary Education Act has had a significant impact on licenses for teachers working in school programs. The act refers to highly qualified teachers in both Title I and Title ll.
Berry, R. Q., III
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Expert assessment as a management tool of secondary school
The essenceof expert evaluationas a tool formanagementof secondary schools has been substantiated. Thecontent of the concepts «expertise», «expert assessment» and «education expert» has been determined.In particular, the education expertise has been ...
Ivanytska Olga, Panchenko Alla
doaj +1 more source
An experience of teacher education on task design in Colombia [PDF]
We describe an experience in task design within an in-service secondary mathematics teacher education program in Colombia. Following a model known as didactic analysis, a team of researchers, educators, mentors and practicing teachers worked together in ...
Gemad, Grupo
core
Maternal thyroid function and child educational attainment: prospective cohort study [PDF]
Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline +7 more
core +3 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
An interview: Making art as a dialogue with materials, moments and motivations [PDF]
Graham Price has worked extensively in primary, secondary and tertiary art education in Otago (1976–1997) and since 2000 in pre-service secondary and primary art education within the University of Waikato arts education team.
Earl Rinehart, (Suzanne) Kerry +1 more
core

