Results 211 to 220 of about 9,246,101 (265)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST. [PDF]

Lancet, The, 1889
n ...
Stephen Paget
exaly   +2 more sources

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Secondary Nucleation and Growth of ZnO

Journal of the American Chemical Society, 2007
Recently we discovered that under certain conditions new crystal growth (branch) can be induced on specific crystalline planes of the same material. This is a new phenomenon and is in sharp contrast to typical nucleation and growth in which a crystal will simply grow larger in preferred directions depending on the surface energy of the specific ...
Thomas L, Sounart, Jun, Liu, James A, Voigt, Mae, Huo, Erik D, Spoerke, Bonnie, McKenzie   +5 more
openaire   +2 more sources

Transcriptional regulation of secondary growth in Arabidopsis thaliana. [PDF]

Journal of Experimental Botany, 2003
Despite its economic and environmental significance, understanding the molecular biology of secondary growth (i.e. wood formation) in tree species has been lagging behind that of primary growth, primarily due to the inherent difficulties of tree biology.
Kyung-Hwan Han, Sunchung Park
exaly   +3 more sources

Secondary Precipitate Growth in Mg-PSZ

Key Engineering Materials, 1991
Magnesia Partially Stabilised Zirconia (Mg-PSZ) is a transformation toughening ceramic with fracture toughness values well above those of traditional ceramic materials. Toughening is achieved by precipitation of the metastable tetragonal phase within the cubic ZrO2-MgO matrix and the growth of these precipitates to a size at which they will transform ...
Hay, S., Nairn, J. D., St. John, D. H.
openaire   +3 more sources

Vegetative Growth and Organogenesis: Branching and Secondary Growth

2023
This chapter surveys vegetative growth by examining the mechanism of branching and secondary growth. It highlights developmental pathways on the branches of shoots and roots and shows how these originate from different structures but converge on a common endpoint, which is the production of new apical meristems which greatly enhances the rate of ...
Lincoln Taiz, Ian Max Møller, Angus Murphy, Eduardo Zeiger   +3 more
openaire   +1 more source

Bubble growth in secondary foams

Chemical Engineering & Technology, 1997
AbstractWhen mechanical foambreakers are used in chemical engineering processes to control an undesired primary foam, a secondary foam is often produced. Secondary foams consist of small bubbles, have a high liquid hold‐up, and cannot be condensed further by mechanical foambreakers.
Stefan Gutwald, Alfons Mersmann
openaire   +1 more source