Results 61 to 70 of about 301,399 (299)
Fremanezumab for the Preventive Treatment of Chronic Migraine. [PDF]
, 2017 BACKGROUND: Fremanezumab, a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP), is being investigated as a preventive treatment for migraine.
Aycardi, Ernesto +9 more
core +2 more sources
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Guideline on the use of onabotulinumtoxinA in chronic migraine. a consensus statement from the European Headache Federation [PDF]
, 2018 OnabotulinumtoxinA is being increasingly used in the management of chronic migraine (CM). Treatment with onabotulinumtoxinA poses challenges compared with traditional therapy with orally administered preventatives.
Ahmed, Fayyaz +8 more
core +3 more sources
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Indian Journal of PainHeadaches in cancer patients can indicate serious conditions such as intracranial metastases, intracranial hypertension, meningeal carcinomatosis, or treatment side effects.
Bilena Margarita Molina-Arteta +3 more
doaj +1 more source
Headaches: new classification, clinical and diagnostic criteria in General Medicine
Clinical Management Issues, 2014 The classification system of headaches is one of the oldest in medicine, and includes a hugeamount of types and causes. The International Headache Society has listed two broad categoriesfor headache disorders: primary headache disorders, which lack a ...
Linda Iurato
doaj +1 more source
Approach to Headache in Patients with COVID-19
Acta Médica Portuguesa, 2021 N/a.
Andreia Costa +2 more
doaj +1 more source
Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke +5 more
wiley +1 more source
Headache as a sign of ear, nose, and throat diseases: evidence from a specialized clinic [PDF]
Health Science MonitorBackground & Aims: Headache has been a common problem for humans since ancient times. The aim of this study was to investigate the prevalence of ear, nose, and throat diseases in patients with headache.
Reza Samarei +2 more
doaj
BiomedicinesBackground: Headache is a common symptom during acute viral infections, and its pathophysiology has been linked with the immune response to the virus. Headache is one of the most frequent symptoms of coronavirus disease 2019 (COVID-19), and it has been ...
Henar Ruiz-Saez +28 more
doaj +1 more source