Results 131 to 140 of about 3,127,419 (312)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Evaluation of firearm injuries by trauma scoring systems in a secondary health care institution. [PDF]
Ulus Travma Acil Cerrahi Derg, 2022 Nusretoğlu R +3 more
europepmc +1 more source
The Effect of Budgets on Doctor Behaviour: Evidence From A Natural Experiment [PDF]
In many health care systems primary care physicians act as 'gatekeepers' to secondary care. We investigates the impact of the UK fundholding scheme under which general practices could elect to hold a budget to meet the costs of elective surgery for their
Hugh Gravelle +3 more
core
GEOSPATIAL ANALYSIS OF PEDIATRIC TUBERCULOSIS IN BOHOL, PHILIPPINES: DISEASE CLUSTERS AND ACCESS TO CARE [PDF]
, 2019 Worldwide, children represent approximately 10% of global tuberculosis (TB) cases. We recently reported a high tuberculin skin test (TST)-positive prevalence (355/5,476; weighted prevalence=6.4%) among children (\u3c15 years) throughout the island of ...
LEINING, LAUREN M
core +1 more source
ENVIRONMENTAL RISKS IN A SERVICE FOR SECONDARY CARE FOR HEALTH
Cogitare Enfermagem, 2013 This research was undertaken with the objective of identifying and quantifying the environmental risks in a service for secondary care for health, taking into account the level of schooling of, and the activities carried out by, the participants of the study, who made up the multidisciplinary team, with a view to contributing to the achieving of better
Juliana Trebi Penatti +4 more
openaire +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Pesquisa Brasileira em Odontopediatria e Clínica IntegradaObjective: To identify the factors associated with the resolution of endodontic treatments in Brazilian municipalities with Brazilian Dental Specialty Centers (CEO).
Albina de Fátima Fanni Santos +2 more
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Primary health care nurses caring for people with diabetes: An integrative review of the literature [PDF]
, 2010 The aim of this integrative literature review was to analyse and synthesize findings from primary empirical studies concerning how nurses in primary care, care for people with diabetes (PWD). Diabetes is a recognized health priority in United Kingdom
Cowley, Julie
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source