Results 41 to 50 of about 3,034,967 (251)

Long‐Term Blood Pressure Variability and Major Adverse Cardiovascular and Cerebrovascular Events After Intracerebral Hemorrhage

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Survivors of intracranial hemorrhage (ICH) are at increased risk for major adverse cardiovascular and cerebrovascular events (MACCE), in the form of recurrent stroke and myocardial Infarction.
Juan Pablo Castello, Kay‐Cheong Teo, Jessica R. Abramson, Sophia Keins, Courtney E. Takahashi, Ian Y. H. Leung, William C. Y. Leung, Yujie Wang, Christina Kourkoulis, Evangelos Pavlos Myserlis, Andrew D. Warren, Jonathan Henry, Koon‐Ho Chan, Raymond T. F. Cheung, Shu‐Leong Ho, M. Edip Gurol, Anand Viswanathan, Steven M. Greenberg, Christopher D. Anderson, Kui‐Kai Lau, Jonathan Rosand, Alessandro Biffi   +21 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Progression of Traumatic Intracerebral Hemorrhage: A Prospective Observational Study

, 2008
Preliminary evidence has shown that intracerebral hemorrhages, either spontaneous (sICH) or traumatic (tICH) often expand over time. An association between hemorrhage expansion and clinical outcomes has been described for sICH.
Servadei, Franco, Skolnick, Brett E., Narayan, Raj K, Tillinger, Michael N, Tillinger, Michael N., and The Traumatic Intracerebral Hemorrhage Study Group, Maas, Andrew I.R, McCarthy, Mary C., Narayan, Raj K., Maas, Andrew I. R., Marshall, Lawrence F., Marshall, Lawrence F, Skolnick, Brett E, Maas, Andrew I.R.   +13 more
core   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Nd:YAG membranotomy for preretinal hemorrhage secondary to valsalva retinopathy [PDF]

, 2014
PurposeTo report four cases of premacular hemorrhage secondary to valsalva retinopathy treated with Nd:YAG membranotomy and discuss techniques as well as the literature.DesignRetrospective case series.MethodsA retrospective review was conducted for four ...
Munie, Metasebia, Ober, Michael D., Desai, Uday, Kuruvilla, Oscar, Miller, Joel A., Shah, Manthan   +5 more
core   +1 more source

Treatments administered to women with secondary postpartum hemorrhage.

, 2022
Treatments administered to women with secondary postpartum hemorrhage.
Natthicha Chainarong (10797945), Kittiya Deevongkij (12174480), Chusana Petpichetchian (10797939)   +2 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Blood levels of Glial Fibrillary Acidic Protein (GFAP) in patients with neurological diseases [PDF]

, 2013
Background and Purpose: The brain-specific astroglial protein GFAP is a blood biomarker candidate indicative of intracerebral hemorrhage in patients with symptoms suspicious of acute stroke.
Niessner, Marion, Robert Brunkhorst, Brunkhorst, Robert, Helmuth Steinmetz, Steinmetz, Helmuth, Marion Niessner, Mayer, Christoph, Christian Foerch, Pfeilschifter, Waltraud, Christoph A Mayer, Förch, Christian, Waltraud Pfeilschifter   +11 more
core   +2 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source