A Case Report of Pulmonary Hypertrophic Osteoarthropathy Secondary to Pulmonary Carcinoma [PDF]
患者,男,54岁,因“指(趾)末端无痛性、进行 性增粗3年,膝、踝关节疼痛伴活动障碍2年”入住天津医 科大学总医院。患者曾先后就诊于内分泌科和血液科, 未明确诊断。自发病以来,无咳嗽、咳痰、咯血、胸痛 等症状。既往体健,吸烟40年,20支/天。其母死于肺 癌。入院查体:甲床无紫绀;双肺呼吸音清,未闻及啰 音;心音有力,律齐,未闻及杂音;明显杵状指(趾) 伴周围皮肤红肿、发亮,皮温稍高,无触痛,呈对称分 布(图1);双侧膝、踝关节轻度肿胀,轻压痛,浮髌 试验阴性。实验室检查:血、尿、便常规、凝血功能、 肝肾功能、电解质以及免疫全项(抗核抗体、类风湿因 子和抗中性粒细胞胞浆抗体)等均正常。双膝X线示: 双侧股骨下端、胫骨上端及腓骨近端可见对称性骨膜增 生,考虑双膝关节肺性肥大性骨关节病(图2)。全身骨 ...
Diansheng ZHONG, Linjuan LIAN, Song WU
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Secondary hypertrophic osteoarthropathy an unusual cause of arthritis in childhood [PDF]
Although an uncommon occurrence in childhood, hypertrophic osteoarthropathy secondary to tumors—most commonly to osteogenic sarcoma with pulmonary metastasis—may cause severe joint pain and swelling.
Adler+14 more
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Hypertrophic pulmonary osteoarthropathy secondary to bronchial adenocarcinoma and coexisting pulmonary tuberculosis: a case report [PDF]
A 44-year-old man presented with painful swelling of wrists and ankles, severe pain at both tibiae, clubbing of fingers and toes and arthritis in wrist and ankle joints.
A Watanabe+9 more
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Hypertrophic Osteoarthropathy: A Secondary Manifestation of Malignant Melanoma [PDF]
Background. Hypertrophic osteoarthropathy (HOA) is a rare finding in the setting of metastatic melanoma. A majority of cases of secondary HOA involve lung malignancies. Evaluation of presenting symptoms such as polyarthralgia and clubbing followed by review of imaging studies are diagnostic steps for HOA. Case Presentation.
Shiva Malaty, Aditya Gupta
openaire +3 more sources
Collagen‐Based Hydrogels for Cartilage Regeneration
This review provided an overview of the progress made in research on collagen hydrogels with chondrocytes or stem cells, comprehensively covered the research progress and clinical applications of collagen‐based hydrogels that integrated inorganic or organic materials. Cartilage regeneration remains difficult due to a lack of blood vessels.
Lihui Sun+9 more
wiley +1 more source
ABSTRACT Degenerative osteoarthritis (OA) is recognized as an early‐onset comorbidity of X‐linked hypophosphatemia (XLH), contributing to pain and stiffness and limiting range of motion and activities of daily living. Here, we extend prior findings describing biochemical and cellular changes of articular cartilage (AC) in the phosphate‐wasting ...
Carolyn M Macica, Steven M Tommasini
wiley +1 more source
Complete form of pachydermoperiostosis with good initial response to etoricoxib: A case report
X‐ray of hand showing cortical thickening and periosteal reaction in distal radius ulna and phalynges of hand of a patient with pachydermoperiostosis. Key Clinical Message Pachydermoperiostosis is a rare genetic disorder that closely resembles acromegaly. Diagnosis is usually based on distinct clinical and radiological features. Oral etoricoxib therapy
Abinash Baniya+6 more
wiley +1 more source
Nosology of genetic skeletal disorders: 2023 revision
Abstract The “Nosology of genetic skeletal disorders” has undergone its 11th revision and now contains 771 entries associated with 552 genes reflecting advances in molecular delineation of new disorders thanks to advances in DNA sequencing technology.
Sheila Unger+20 more
wiley +1 more source
Osteological and Biomolecular Evidence of a 7000-Year-Old Case of Hypertrophic Pulmonary Osteopathy Secondary to Tuberculosis from Neolithic Hungary [PDF]
Seventy-one individuals from the late Neolithic population of the 7000-year-old site of Hódmezővásárhely-Gorzsa were examined for their skeletal palaeopathology.
Besra, GS+8 more
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A case report of an extremely rare association of ankylosing spondylitis with pachydermoperiostosis
Key Clinical Message We describe a case of a young man with features of pachydermoperiostosis and spondyloarthropathy. By describing this rarity, we aim to help build a database for future studies and construct a management plan that rheumatologists and clinicians can use.
Faiq I. Gorial+2 more
wiley +1 more source