Results 11 to 20 of about 692 (129)
Thoracic Cancer, Volume 14, Issue 14, Page 1320-1324, May 2023., 2023 Lung cancer cells express vascular endothelial growth factor (VEGF), possibly releasing it into the circulation. The hypoxic tumor microenvironment may have caused some lung cancer cells to express hypoxia‐inducible factor‐1α (HIF‐1α), which contributes, at least in part, to VEGF production.
Ryuta Tagawa +12 more
wiley +1 more source
Pierre Marie–Bamberger syndrome (secondary hypertrophic osteoarthropathy) [PDF]
International Journal of Dermatology, 2004 A 55‐year‐old man presented to our Department with a 10‐year history of coarsening of the facial features. The soft tissue of the forehead had become progressively thickened and corrugated, resulting in marked, hard‐elastic asymmetrical convolutions involving the underlying eyelids, with partial reduction of the visual field (Fig. 1a,b).
CANNAVO', Serafinella +3 more
openaire +4 more sources
Advanced Science, Volume 10, Issue 10, April 5, 2023., 2023 The SIRT3‐medicated post‐translational acetylation of the mitochondrial respiratory chain has therapeutic potential for the treatment of osteoarthritis (OA). Mechanistically, SIRT3 directly binds and deacetylates COX4I2 to promote mitochondrial respiration activity.
Yijian Zhang +12 more
wiley +1 more source
High Bone Mass Disorders: New Insights From Connecting the Clinic and the Bench
Journal of Bone and Mineral Research, Volume 38, Issue 2, Page 229-247, February 2023., 2023 ABSTRACT Monogenic high bone mass (HBM) disorders are characterized by an increased amount of bone in general, or at specific sites in the skeleton. Here, we describe 59 HBM disorders with 50 known disease‐causing genes from the literature, and we provide an overview of the signaling pathways and mechanisms involved in the pathogenesis of these ...
Dylan J.M. Bergen +19 more
wiley +1 more source
CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis
Orthopaedic Surgery, Volume 14, Issue 5, Page 946-954, May 2022., 2022 CD38 is a membrane‐bound protein. This study primarily implicates CD38 as an important regulator of chondrogenic differentiation. Inhibition of CD38 demonstrated protection against cartilage degeneration, which suggests that CD38 could be a potential therapeutic target for OA.
Jin‐jin Ma +9 more
wiley +1 more source
Mouse models of patent ductus arteriosus (PDA) and their relevance for human PDA
Developmental Dynamics, Volume 251, Issue 3, Page 424-443, March 2022., 2022 Key Findings Mouse models of patent ductus arteriosus (PDA) are informative for human PDA. Human single‐gene disorders with a PDA phenotype reveal interacting networks that contribute to regulation of DA patency and closure. Cross‐species correlations identify pathways of interest for development of PDA therapeutics. Abstract The ductus arteriosus (DA)
Michael T. Yarboro +4 more
wiley +1 more source
, 2023 HemaSphere, Volume 7, Issue S3, August 2023.
Ganesh Kumar Viswanathan +6 more
wiley +1 more source
JGH Open, Volume 6, Issue 2, Page 100-111, February 2022., 2022 Immune‐mediated inflammatory diseases (IMIDs) of the gastrointestinal tract including inflammatory bowel disease (IBD) are a diverse group of complex inflammatory diseases that share similar pathophysiology. IMIDs other than IBD can have similar clinical features causing diagnostic and therapeutic challenges.
Sudheer K Vuyyuru +3 more
wiley +1 more source
A Rare Cause of Refractory Anaemia hidden between Folds
, 2023 British Journal of Haematology, Volume 202, Issue 4, Page 712-712, August 2023.
Syna Hamani +3 more
wiley +1 more source
Clinical Case Reports, Volume 10, Issue 1, January 2022., 2022 Schizophrenia is associated to somatic diseases. We describe an association with hypertrophic osteoarthropathy (HPO). It is a rare clinical entity but it could be a paraneoplastic syndrome hiding a life‐threatening condition. Abstract Schizophrenia is associated to somatic disorders especially cardio‐vascular and auto‐immune.
Emna Baklouti +3 more
wiley +1 more source