Results 231 to 240 of about 1,238,736 (354)

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim, Ning Guo, Zong Yao Tan, Xing Gao, Pouria Fattahi, Haijiao Liu, Jeehan Chang, Mousa Younesi, Selice Jung, Yewhan Chung, Minkyung Song, Michelle Jung, Dan Dongeun Huh   +12 more
wiley   +1 more source

The secondary metabolism collaboratory: a database and web discussion portal for secondary metabolite biosynthetic gene clusters. [PDF]

Nucleic Acids Res
Udwary DW, Doering DT, Foster B, Smirnova T, Kautsar SA, Mouncey NJ.   +5 more
europepmc   +1 more source

Roles of a 20 kDa Protein Associated with a Carbocycle-Forming Enzyme Involved in Aminoglycoside Biosynthesis in Primary and Secondary Metabolism [PDF]

, 2010
Hideyuki Tamegai, Hiroshi Sawada, Eriko Nango, Rie Aoki, Haruka Hirakawa, Teruhiko Iino, Tadashi Eguchi   +6 more
openalex   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Unveiling the Role of β-Glucosidase Genes in Bletilla striata's Secondary Metabolism: A Genome-Wide Analysis. [PDF]

Int J Mol Sci
Xu M, Li H, Luo H, Liu J, Li K, Li Q, Yang N, Xu D.   +7 more
europepmc   +1 more source

Impact of Ammonium Permeases MepA, MepB, and MepC on Nitrogen-Regulated Secondary Metabolism in Fusarium fujikuroi

, 2007
Sabine Teichert, Julian C. Rutherford, Marieke Wottawa, Joseph Heitman, Bettina Tudzynski   +4 more
openalex   +1 more source

Heterochromatic marks are associated with the repression of secondary metabolism clusters in Aspergillus nidulans [PDF]

, 2010
Yazmid Reyes-Domínguez, Jin Woo Bok, Harald Berger, E. Keats Shwab, Asjad Basheer, Andreas Gallmetzer, Claudio Scazzocchio, Nancy P. Keller, Joseph Strauss   +8 more
openalex   +1 more source

Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa, Ana Marote, Catarina Barbosa, Jonas Campos, António J. Salgado, Jana B. Nieder   +5 more
wiley   +1 more source

RNA-Seq Insight into the Impact and Mechanisms of Methyl Donor and Glycine Betaine Osmoprotectant on Polyketide Secondary Metabolism in <i>Monascus purpureus</i> M1. [PDF]

J Fungi (Basel)
Liu Z, Zhang H, Xue F, Niu L, Qi C, Chen W, Zheng J, Wang C.   +7 more
europepmc   +1 more source

cAMP signalling is involved in growth, germination, mycoparasitism and secondary metabolism in Trichoderma virens

, 2007
Shatavisa Mukherjee, Prasun K. Mukherjee, S. P. Kale   +2 more
openalex   +1 more source