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Molecular recognition by secondary metabolites

Biochemical Pharmacology, 1990
Aspects of molecular recognition based on the interaction between the vancomycin group of antibiotics and bacterial cell wall precursor analogues are discussed. The energetically unfavourable folding-in of the residue 1 sidechain in vancomycin and ristocetin A is discussed in terms of the favourable entropy associated with simultaneous release of ...
D H, Williams   +3 more
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Extraction of Plant Secondary Metabolites

2006
This chapter presents an overview of the preparation of extracts from plants using organic solvents, with emphasis on common problems encountered and methods for their reduction or elimination. In addition to generally applicable extraction protocols, methods are suggested for selectively extracting specific classes of plant-derived compounds, and ...
William P, Jones, A Douglas, Kinghorn
openaire   +2 more sources

Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review.

Carbohydrate Polymers, 2020
Wound healing can lead to complex clinical problems, hence finding an efficient approach to enhance the healing process is necessary. An ideal wound dressing should treat wounds at reasonable costs, with minimal inconveniences for the patient.
A. Moeini   +4 more
semanticscholar   +1 more source

Detection of Novel Secondary Metabolites

Critical Reviews in Biotechnology, 1991
The study of antibiotics and other fermentation products has shown that a seemingly unlimited number of compounds with diverse structures are produced by microorganisms. The continued high rate of discovery of new chemical entities, in the light of the abundance of microbial products already described, is due to creative screening procedures that ...
C M, Franco, L E, Coutinho
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Redox active secondary metabolites

Current Opinion in Chemical Biology, 2011
Various secondary metabolites from plants, bacteria and fungi are redox active and able to modulate the intracellular redox equilibrium in living cells. Many of these compounds behave as antioxidants, yet some of them also cause oxidative modifications, which may ultimately result in cell death.
Claus, Jacob   +2 more
openaire   +2 more sources

Unexpected applications of secondary metabolites

Biotechnology Advances, 2011
Secondary metabolites have been found to have interesting applications over and above their well-known medical uses, e.g., as antimicrobials, etc. These alternative applications include antitumor, cholesterol-lowering, immunosuppressant, antiprotozoal, antihelminth, antiviral and anti-ageing activities.
Preeti, Vaishnav, Arnold L, Demain
openaire   +2 more sources

Production of Secondary Metabolites by Bioconversion

2007
The omnipotency (omnis = all, potens = powerful) of the plant cell implies that all genetic information present in the plant is principally available in each cell. This means that genes encoding enzymes that belong to biosynthetic pathways can be brought to expression.
Pras, Niesko, Woerdenbag, Herman J.
openaire   +3 more sources

The physiology and biosynthesis of secondary metabolites

Acta Biologica Hungarica, 1997
Recently, several excellent reviews appeared /9, 12, 15, 29/ summarizing new findings of the last years and describing the topic in the new interconnections. The signalling systems through which changes in environmental conditions affecting the growth of microorganism are sensed, transmitted and converted into mechanisms controlling the production of ...
Z, Vanek, J, Janecek
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Secondary metabolites for antiulcer activity

Natural Product Research, 2015
Peptic ulcers are open sores or erosions in the lining of either the duodenum (duodenal ulcers) or the stomach (gastric ulcers). Peptic ulcer, which is mainly caused by bacterial attack or excess of acid secretion, can be cured effectively by these isolated plant compounds.
openaire   +2 more sources

Mutation and the Production of Secondary Metabolites

1973
Publisher Summary This chapter deals with microbially produced secondary metabolites. Secondary metabolites are a group of products that are extremely important to health and nutrition. They are usually produced during the idiophase of development, have no general function in growth processes, are produced by certain restricted taxonomic groups of ...
openaire   +2 more sources

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