Results 81 to 90 of about 1,706,928 (311)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Identifying the secondary school students’ misconceptions about functions
Procedia - Social and Behavioral Sciences, 2011 AbstractIt is very important to identify and correct the mistakes that students make about mathematical concepts. The purpose of this study is to detect the secondary school students’ misconceptions about functions in the 2009-2010 academic year .Research data was collected 61 students, included 9th,10th and 11th grade students selected randomly, in ...
ŞÜKRÜ, CANSIZ +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
TOBACCO SMOKING HABITS OF SECONDARY SCHOOL STUDENTS
Health Problems of Civilization, 2023 Gabriel Dziura +1 more
doaj +1 more source
School Identity of Secondary Technical Schools Students and University Students
Lifelong Learning, 2017 The study describes the development of school identity among young people, it focuses on its two main processes, namely the exploration of the study and commitment to study. The research goal of the study was to determine the role of the type of the school and subjective perception of the study in these processes.
Lucia Kvitkovičová, Jana Máchová
openaire +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Bio-Psycho-Motor Aspects of Secondary School Students
ACROSS, 2022 The human is the product of the specific interaction of natural and social factors. Periods of age were divided by specialists differently; Demeter, A.
Vasile TRIBOI, Natalia NASTAS
doaj
Transition Planning -- Responsibilities and Strategies [PDF]
, 2011 This meta-synthesis of the literature, on transition planning for youth with disabilities, examines several important facets that impact the post school outcomes for students with disabilities.
Arnold, Art
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Computers, the internet, and cheating among secondary school students: Some implications for educators [PDF]
, 2004 This article investigates in greater depth one particular aspect of cheating within secondary education and some implications for measuring academic achievement.
Conradson, Stacey +1 more
core +1 more source