Results 61 to 70 of about 6,029,052 (258)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Stability and change of motivation profiles in mathematics instruction in lower secondary education

open access: yes, 2021
Motivation is an important factor for successful learning processes and outcomes. Given the heterogeneity of individuals, it is of particular importance to understand differences between learners by applying a person-centered approach. The first research
Held, Tanja, Hascher, Tina
core  

Tree slenderness and stability of Brazilian pine in a secondary forest [PDF]

open access: yesFloresta e Ambiente
The aim of this study was investigating the factors that render Araucaria angustifolia trees less stable in secondary forests to support the species conservation strategies.
Vinicius Costa Cysneiros   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

National Center on Secondary Education and Transition (NCSET): An Overview [PDF]

open access: yes, 2015
An overview describing the National Center on Secondary Education and Transition (NCSET) at the University of Minnesota's Institute on Community Integration.National Center on Secondary Education and Transition. (2015).
National Center on Secondary Education and Transition
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Caviar Diplomacy

open access: yes, 2012
European Stability ...
European Stability Initiative
core  

Stiffness and strength of shear diaphragms used for stability bracing of slender beams

open access: yes, 2014
Structural Stability Research Council Annual Stability Conference 2014, SSRC 2014; Toronto, ON; Canada; 25 March 2014 through 28 March 2014Light gage metal decking is often used in structures as concrete deck formwork, roof cladding or siding.
Vardaroğlu, Mustafa   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Stability Analysis of the Secondary Motion of a Textured Piston

open access: yesLubricants
Piston–cylinder pairs are very common in industrial mechanisms. While a piston is primarily designed for axial reciprocating motion, the occurrence of secondary motions—lateral and rotational—due to the small clearance between the piston and the cylinder
Igal Cohen   +2 more
doaj   +1 more source

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