Results 71 to 80 of about 306,585 (324)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Cooperative Secret Communication with Artificial Noise in Symmetric Interference Channel
, 2010 We consider the symmetric Gaussian interference channel where two users try to enhance their secrecy rates in a cooperative manner. Artificial noise is introduced along with useful information.
Mo, Jianhua, Tao, Meixia, Zhu, Jingge
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Performance Philosophy, 2017 The following text opened the conference, “The Concept of Immanence in Philosophy and the Arts”, held in Vienna in May 2016. It is a reader consisting of key passages on immanence by Gilles Deleuze, Baruch de Spinoza, Giorgio Agamben, Henri Bergson ...
Alice Lagaay, Susanne Valerie Granzer
doaj +1 more source
Congressional Lawmaking: A Perspective On Secrecy and Transparency [PDF]
, 2011 [Excerpt] Openness is fundamental to representative government. Yet the congressional process is replete with activities and actions that are private and not observable by the public.
Oleszek, Walter J
core +2 more sources
Optimal Number of Transmit Antennas for Secrecy Enhancement in Massive MIMOME Channels
, 2017 This paper studies the impact of transmit antenna selection on the secrecy performance of massive MIMO wiretap channels. We consider a scenario in which a multi-antenna transmitter selects a subset of transmit antennas with the strongest channel gains ...
Asaad, Saba +4 more
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Secrecy Results for Compound Wiretap Channels
, 2012 We derive a lower bound on the secrecy capacity of the compound wiretap channel with channel state information at the transmitter which matches the general upper bound on the secrecy capacity of general compound wiretap channels given by Liang et al. and
AD Wyner +18 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
EU Institutional Politics of Secrecy and Transparency in Foreign Affairs: A Commentary
Politics and Governance, 2017 International diplomacy has long been regarded as the domain of an elite hand-picked few, instructed and groomed in something considered an art form. Both the secrecy and the pomp have their rational place.
Emily O'Reilly
doaj +1 more source