Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
On the Secrecy Rate of Multi-antenna Wiretap Channel under Finite-alphabet Input
This work investigates the effect of limiting source signals to finite-alphabet on the secrecy rate of a multi-antenna wiretap system. Existing works have characterized maximum achievable secrecy rate or secrecy capacity for single- and multi-antenna ...
Xiao, Chengshan +2 more
core +2 more sources
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
Secrecy Rate Optimizations for a MIMO Secrecy Channel with a Multiple-Antenna Eavesdropper
This paper studies different secrecy rate optimization problems for a multiple input multiple output (MIMO) secrecy channel. In particular, we consider a scenario where a communication through a MIMO channel is overheard by a multiple-antenna ...
Tian GY +4 more
core
Secure Satellite Communication Systems Design With Individual Secrecy Rate Constraints
In this paper, we study multibeam satellite secure communication through physical (PHY) layer security techniques, i.e., joint power control and beamforming.
María Ángeles Vazquez-Castro +7 more
core +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Ergodic Secrecy Rate Analysis for LEO Satellite Downlink Networks
Satellite networks are recognized as an effective solution to ensure seamless connectivity worldwide, catering to a diverse range of applications. However, the broad coverage and broadcasting nature of satellite networks also expose them to security ...
Kim, Daeun, Lee, Namyoon
core +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
On the Sum Secrecy Rate Maximisation for Wireless Vehicular Networks
Wireless communications form the backbone of future vehicular networks, playing a critical role in applications ranging from traffic control to vehicular road safety. However, the dynamic structure of these networks creates security vulnerabilities, making security considerations an integral part of network design.
Muhammad Farooq 0002 +3 more
openaire +2 more sources

