Results 121 to 130 of about 51,505 (219)

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, EarlyView.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, Volume 7, Issue 2, March 2026.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin. [PDF]

Cell Res, 2020
Wang Y, Wang G, Li Y, Zhu Q, Shen H, Gao N, Xiao J.   +6 more
europepmc   +1 more source

Non‐Starch Purple Sweet Potato Polysaccharide Ameliorates Lipopolysaccharides‐Induced Acute Colitis by Regulating Gut Function and Inactivating the NOD‐Like Receptor Protein 3 Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
Purple sweet potato polysaccharide (PSP) ameliorates lipopolysaccharide‐induced ulcerative colitis in mice through multiple coordinated mechanisms. Oral PSP administration dose‐dependently: (1) Modulates gut microbiota composition and increases short‐chain fatty acid levels; (2) strengthens intestinal barrier function; (3) attenuates systemic ...
Peng Yu, Jitao Ling, Yixuan Chen, Panpan Xia, Yuting Wu, Jianqi Liang, Xuehong Zheng, Yunkun Liu, Zhou Xu, Yiming Gan, Ao Shi, Wenting Wang, Xiao Liu, Yaqi Rong, Yan Xiong, Jianping Liu, Xiaoping Yin, Jing Zhang, Deju Zhang   +18 more
wiley   +1 more source

Short-term storage conditions do not affect canine fecal cortisol and secretory immunoglobulin A concentrations. [PDF]

Sci Rep
Lenz OC, Powell L, Reinhard CL, Watson B.   +3 more
europepmc   +1 more source

Non-Secretory Myeloma With Non-Producing Phenotype Presented as Plasma Cell Leukaemia With Plasmablast Morphology. [PDF]

EJHaem
eJHaem, Volume 7, Issue 1, February 2026.
Xu K, Proctor I.
europepmc   +2 more sources

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Effect of a Multi-Strain Probiotic on Secretory Immunoglobulin-A Levels in Patients with Complete Edentulism: A Quasi-Experimental Study. [PDF]

J Int Soc Prev Community Dent
Kaur H, Dhawan P, Mahesh S, Gupta N.
europepmc   +1 more source

No Impact of Long-Term Fingolimod Treatment on Fecal Secretory Immunoglobulin A Levels in Patients With Multiple Sclerosis. [PDF]

Front Cell Dev Biol, 2020
Inojosa H, Eisele J, Proschmann U, Zeissig S, Akgün K, Ziemssen T.   +5 more
europepmc   +1 more source

Dysregulated proteolytic cascades in Netherton syndrome: from molecular pathology to preclinical drug testing

The Journal of Pathology, Volume 268, Issue 3, Page 249-262, March 2026.
Abstract Netherton syndrome (NS) is a rare, severe, and often life‐threatening disease for which current therapeutic approaches are limited and show variable effectiveness. NS is characterized by excessive epidermal desquamation that results in a highly defective epidermal barrier, constitutive skin inflammation, allergies, and hair abnormalities.
Eleni Zingkou, Evangelos Bisyris, Georgios Pampalakis, Georgia Sotiropoulou   +3 more
wiley   +1 more source