Results 151 to 160 of about 51,505 (219)

Discovery of Lomitapide as a Novel Mast Cell Regulatory Agent Through Chemical Library Screening

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Chemical library screening identified lomitapide as a novel mast cell (MC) regulatory agent. Lomitapide selectively inhibits IgE/Ag‐ or phorbol 12‐myristate 13‐acetate (PMA)/ionomycin‐mediated MC degranulation by altering plasma membrane dynamics, including endocytosis and membrane fusion. ABSTRACT Allergic diseases are a global health concern, and new
Shiori Mamorita   +3 more
wiley   +1 more source

Nexus of Whey Proteins, Gut Dysbiosis, and Colonic Health

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Whey proteins possess antimicrobial and prebiotic properties that modulate gut microbiota by promoting beneficial bacteria like Bifidobacterium while suppressing pathogens. This modulation enhances short‐chain fatty acid production and strengthens intestinal barrier integrity, potentially alleviating dysbiosis‐related conditions such as colitis and ...
Tolulope Joshua Ashaolu   +4 more
wiley   +1 more source

Clinical Analysis of Neonatal Influenza in the Neonatal Intensive Care Unit: A Retrospective Study

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background To describe the clinical characteristics, treatment, and outcomes of neonatal influenza. Methods Retrospectively analyzed clinical data on 26 neonates who were diagnosed with neonatal influenza by positive influenza nasopharyngeal swab antigen tests, and admitted to the neonatal intensive care unit of Sichuan Province Chengdu ...
Min Zhou   +5 more
wiley   +1 more source

Lack of Gut Secretory Immunoglobulin A in Memory B-Cell Dysfunction-Associated Disorders: A Possible Gut-Spleen Axis. [PDF]

open access: yesFront Immunol, 2019
Carsetti R   +15 more
europepmc   +1 more source

Secretory immunoglobulin A and intestinal diseases

open access: yesWorld Chinese Journal of Digestology, 2017
Bo Han   +5 more
openaire   +1 more source

T‐Cell‐Derived Exosomes From Multi Core Granules Exhibit Superior Caspase‐3‐Mediated Tumor‐Suppressive Activity Compared to Those From Multivesicular Bodies

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT Small extracellular vesicles (sEVs) derived from cytotoxic T lymphocytes (CTLs) are emerging as potential mediators of antitumor immunity; however, their subcellular origins and functional properties remain incompletely defined. In this study, we investigated the intracellular routes and cytotoxic potential of CTL‐derived exosomes.
Nadia Alawar   +10 more
wiley   +1 more source

Subthreshold eosinophilia during food impaction may mask eosinophilic esophagitis: A pediatric case series

open access: yesJPGN Reports, Volume 7, Issue 1, Page 127-131, February 2026.
Abstract To describe the clinical scenario and need for longitudinal follow‐up of pediatric patients presenting with esophageal food impactions (EFIs) regardless of esophageal biopsy eosinophil count. A retrospective chart review was conducted on patients with EFI who underwent endoscopic evaluation from August 2022 to August 2024.
Mark Mahon, Amanda Muir
wiley   +1 more source

Home - About - Disclaimer - Privacy