Results 111 to 120 of about 17,164,709 (325)
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Flexible thermal apparatus for mounting of thermoelectric cooler [PDF]
A flexible heat transfer apparatus used to flexibly connect and thermally couple a thermoelectric cooler to an object to be cooled is disclosed. The flexible heat transfer apparatus consists of a pair of flexible corrugated sheets made from high thermal ...
Bard, Steven +2 more
core +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
"Mama, Do You Love Me?": A Defense of Unloving Parents [PDF]
In this chapter I critique the contemporary Western ideal of unconditional maternal love. In the first section, I draw some preliminary distinctions and clarify the scope and limitations of my inquiry. In the second section, I argue that unloving mothers
Protasi, Sara
core
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Two interesting annual Silene species (Caryophyllaceae) reported for the flora of Iran
In a revision of annual Silene species some interesting specimens were observed, which belonged to the sp-ecies that had not been previously reported in detail from Iran. In this paper S.
Abbas Gholipour, Masume Golshahi
doaj
Sorbaria sorbifolia var. glandulifolia, endemic to Korea, is distinguished by glandular trichomes on the abaxial leaflet surface. In this study, we present its first complete chloroplast genome (159,476 bp) with a typical quadripartite structure ...
Young-Kee Kim +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

