Results 71 to 80 of about 14,239,838 (283)

On the number of diamonds in the subgroup lattice of a finite abelian group

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2016
The main goal of the current paper is to determine the total number of diamonds in the subgroup lattice of a finite abelian group. This counting problem is reduced to finite p-groups. Explicit formulas are obtained in some particular cases.
Fodor Dan Gregorian   +1 more
doaj   +1 more source

"Mama, Do You Love Me?": A Defense of Unloving Parents [PDF]

open access: yes, 2018
In this chapter I critique the contemporary Western ideal of unconditional maternal love. In the first section, I draw some preliminary distinctions and clarify the scope and limitations of my inquiry. In the second section, I argue that unloving mothers
Protasi, Sara
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Calculation of Technological Consumption (Loss) of Electricity in Modern 0.38–10 kV Electrical Distribution Networks

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2018
. New conditions of functioning of electric power industry, tougher of requirements to technological condition of the industry predetermined transition to restructuring of electric networks on the basis of innovative structure of SMART GRID.
M. I. Fursanov   +2 more
doaj   +1 more source

Empathy, Asymmetrical Reciprocity, and the Ethics of Mental Health Care [PDF]

open access: yes, 2018
I discuss Young’s “asymmetrical reciprocity” and apply it to an ethics of mental health care. Due to its emphasis on engaging with others through respectful dialogue in an inclusive manner, asymmetrical reciprocity serves as an ...
Molas, Andrew
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

DEVELOPMENT OF SOME REVOLUTION SURFACES

open access: yesJournal of Industrial Design and Engineering Graphics, 2015
The paper work proposes practical graphic methods provided by Descriptive Geometry to plot the development of two revolution surfaces: the revolution surface having an oval as median section and the revolution surface having an ordinary curve as median ...
Vanda Danaila, Alina Angelica Anghel
doaj   +2 more sources

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