Results 161 to 170 of about 2,562,861 (296)

Bulletin de l'Association Amicale des Anciens et Anciennes Élèves des Sections Normales et de l'École Normale Supérieure de l'Enseignement Technique n° 56

, 1937
28 et 29 Mai 1937 45e Anniversaire des Sections Normales et VINGT-CINQUIÈME ANNIVERSAIRE de L'ÉCOLE NORMALE SUPÉRIEURE DE L'ENSEIGNEMENT ...
Association Amicale des Anciens et Anciennes Élèves des Sections Normales et de l'ENSET
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

An integrated multiscale imaging workflow to resolve intracellular co-pathology in human FFPE brain tissue. [PDF]

Free Neuropathol
Schreiner S, de la Maza MM, Darricau M, Bouvier DS.   +3 more
europepmc   +1 more source

Section News--Section B (Physics) [PDF]

Science, 1979
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Comparative analysis of gene expression in mammalian claustrum subdivisions. [PDF]

PNAS Nexus
Fang C, Li M, Li L, Liang F, Huang J, Lu L, Lu Z, Wang H, Naumann RK.   +8 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Ex vivo comparison of ACU193 and lecanemab reveals binding differences in mouse brain. [PDF]

Alzheimers Dement
Grenon MB, Cline EN, Jerecic J, Johnson E, Siemers E, Lemere CA.   +5 more
europepmc   +1 more source

Failure analysis in postbuckled composite T-sections

, 2008
Blade-stiffened skin designs made of composite materials have the potential to produce highly efficient structures, when the large strength reserves in the postbuckling range are utilised.
Adrian Orifici (18030625), Andrey Kotler (20013588), Tanchum Weller (20009871), Sawan Shah (20013585), I Herszberg (19984140)   +4 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source