Results 221 to 230 of about 334,100 (261)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

The perceived impact of the COVID-19 pandemic on child protective services in Saudi Arabia. [PDF]

Front Public Health
Aleissa M, Alhowaish N, Almutairi W, Alangari AS, Shaheen NA, Abdelhamid R, Ronzoni AR, Boles DGS, Sakr H.   +8 more
europepmc   +1 more source

Escolarització dels infants de 0 a 3 anys [PDF]

, 2006
Albaigés, Bernat, Bonal, Xavier
core   +1 more source

FIRE‐GNN: Force‐Informed, Relaxed Equivariance Graph Neural Network for Rapid and Accurate Prediction of Surface Properties

Advanced Intelligent Discovery, EarlyView.
This study introduces FIRE‐GNN, a force‐informed, relaxed equivariant graph neural network for predicting surface work functions and cleavage energies from slab structures. By incorporating surface‐normal symmetry breaking and machine learning interatomic potential‐derived force information, the approach achieves state‐of‐the‐art accuracy and enables ...
Circe Hsu, Claire Schlesinger, Karan Mudaliar, Jordan Leung, Robin Walters, Peter Schindler   +5 more
wiley   +1 more source

From egalitarianism to veiled selectivity: education, social mobility and the reproduction of inequalities in contemporary Argentina. [PDF]

Front Sociol
Ziegler S, Giovine M.
europepmc   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Professionalism and e-Professionalism From Dentists' Perspective: A Multicenter Cross-Sectional Study. [PDF]

Int J Dent
Alamoush RA, Alaqeely R, Al-Nasrawi SJ, Haider J, Mar'i M, Alkhader R, Al-Omiri MK.   +6 more
europepmc   +1 more source

Consideracions sobre el present i el futur de la cultura a Tarragona [PDF]

, 2005
Cavallé Busquets, Joan
core  

Large Language Model‐Based Chatbots in Higher Education

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci, Merve Eryilmaz, Ail K. Yetisen, Savas Tasoglu, Aydogan Ozcan   +4 more
wiley   +1 more source

A parallel private-pay system will worsen access to publicly funded surgery. [PDF]

CMAJ
Mayall RM, Hastings SE, Manns BJ.
europepmc   +1 more source