Results 111 to 120 of about 13,150 (224)

Exploring longitudinal relationships among Alzheimer's disease biomarkers

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION While most studies of Alzheimer's disease (AD) examine cross‐sectional relationships among biomarkers, longitudinal relationships are also highly relevant. METHODS This study in the Alzheimer's Disease Neuroimaging Initiative cohort (n = 373) used non‐parametric Spearman correlations to explore the relationships of baseline values
Benjamin Saef   +25 more
wiley   +1 more source

Epigenetic aging in Alzheimer's disease: Relation to proteome

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) arises from heterogeneous biological processes, and long‐term environmental exposures may become biologically embedded, as reflected in epigenetic clocks. METHODS We calculated blood DNA methylation‐based epigenetic clocks and constructed protein co‐abundance networks of cerebrospinal fluid (CSF ...
Bo‐Hyun Kim   +5 more
wiley   +1 more source

APOE and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of APP, with and without Down syndrome

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION An extra copy of the amyloid precursor protein (APP) gene causes autosomal dominant Alzheimer's disease (AD) and AD in Down syndrome (DS), but the factors underlying variability in age at onset (AAO) remain unclear. We investigated whether sporadic AD risk variants modify AAO. METHODS We analyzed clinical and genetic data from 100
Joan Groeneveld   +39 more
wiley   +1 more source

Costo directo de cesáreas y reembolso del Seguro Integral de Salud: El caso del Hospital de Apoyo Pomabamba, Ancash, Perú

open access: yesRevista Médica Herediana, 2009
Objetivo: Determinar el costo directo de la cesárea y el porcentaje de reembolso realizado por el Seguro Integral de Salud (SIS), en el Hospital de Apoyo Pomabamba (HAP), en Ancash.
Gladys Moncada Vega   +2 more
doaj  

Analysis of anxiety levels and perceived satisfaction after a first encounter with human body prosection among nursing undergraduates based on their self‐perceived presession nervousness: An observational study

open access: yesAnatomical Sciences Education, Volume 19, Issue 8, Page 1238-1247, August 2026.
Abstract Human body prosection practices are a crucial educational tool for learning anatomy. However, the first exposure to donors' material can cause anxiety, which may affect students' learning experiences and emotional adjustment. This observational study aimed to analyze anxiety levels (state and trait) before and after a prosection session in ...
Mónica Grande‐Alonso   +8 more
wiley   +1 more source

Molecular Ontology Predicts Output Connections From the Nucleus of the Solitary Tract

open access: yesJournal of Comparative Neurology, Volume 534, Issue 8, August 2026.
The nucleus of the solitary tract (NTS) integrates visceral inputs to coordinate appetite and digestion, breathing, and cardiorespiratory reflexes. Using cell‐type‐specific tracing, we show that excitatory Lmx1b neurons project broadly to brainstem and forebrain targets, whereas inhibitory output remains largely brainstem‐restricted. Catecholaminergic (
Silvia Gasparini   +5 more
wiley   +1 more source

Regional Functional Molecular Profiles Within the Mammalian Cortex: A Commentary on Limbic Mesocortex

open access: yesJournal of Comparative Neurology, Volume 534, Issue 8, August 2026.
Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
wiley   +1 more source

The Impact of Denoising Approaches on the Relationship Between Alzheimer's Disease Diagnostic Status and Network Topology Measures

open access: yesHuman Brain Mapping, Volume 47, Issue 11, 01 August 2026.
We examined the influence of denoising approaches on diagnostic differences in network topology across the Alzheimer's disease continuum. We show that the directionality of the diagnostic differences in network topology, particularly in global metrics of network segregation, can vary based upon the denoising approach employed.
Jenna K. Blujus   +2 more
wiley   +1 more source

Salud, juego y comunicación en sectores populares

open access: yesRIDAS. Revista Iberoamericana de Aprendizaje Servicio, 2018
El objetivo del presente trabajo es dar a conocer una experiencia interdisciplinaria y la sistematización de dos programas universitarios donde se aplica el aprendizaje servicio en relación a la prevención del dengue. La metodología utilizada durante el trabajo de campo es cualitativa y flexible porque no se busca la contrastación empírica sino ...
Abreu, Lucía   +4 more
openaire   +1 more source

The X‐Ray Crystal Structure of BorF, the Flavin Reductase Subunit of a Two‐Component Flavin‐Dependent Tryptophan Halogenase

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 8, Page 1529-1540, August 2026.
ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma   +3 more
wiley   +1 more source

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