Results 111 to 120 of about 13,150 (224)
Exploring longitudinal relationships among Alzheimer's disease biomarkers
Abstract INTRODUCTION While most studies of Alzheimer's disease (AD) examine cross‐sectional relationships among biomarkers, longitudinal relationships are also highly relevant. METHODS This study in the Alzheimer's Disease Neuroimaging Initiative cohort (n = 373) used non‐parametric Spearman correlations to explore the relationships of baseline values
Benjamin Saef +25 more
wiley +1 more source
Epigenetic aging in Alzheimer's disease: Relation to proteome
Abstract INTRODUCTION Alzheimer's disease (AD) arises from heterogeneous biological processes, and long‐term environmental exposures may become biologically embedded, as reflected in epigenetic clocks. METHODS We calculated blood DNA methylation‐based epigenetic clocks and constructed protein co‐abundance networks of cerebrospinal fluid (CSF ...
Bo‐Hyun Kim +5 more
wiley +1 more source
Abstract INTRODUCTION An extra copy of the amyloid precursor protein (APP) gene causes autosomal dominant Alzheimer's disease (AD) and AD in Down syndrome (DS), but the factors underlying variability in age at onset (AAO) remain unclear. We investigated whether sporadic AD risk variants modify AAO. METHODS We analyzed clinical and genetic data from 100
Joan Groeneveld +39 more
wiley +1 more source
Objetivo: Determinar el costo directo de la cesárea y el porcentaje de reembolso realizado por el Seguro Integral de Salud (SIS), en el Hospital de Apoyo Pomabamba (HAP), en Ancash.
Gladys Moncada Vega +2 more
doaj
Abstract Human body prosection practices are a crucial educational tool for learning anatomy. However, the first exposure to donors' material can cause anxiety, which may affect students' learning experiences and emotional adjustment. This observational study aimed to analyze anxiety levels (state and trait) before and after a prosection session in ...
Mónica Grande‐Alonso +8 more
wiley +1 more source
Molecular Ontology Predicts Output Connections From the Nucleus of the Solitary Tract
The nucleus of the solitary tract (NTS) integrates visceral inputs to coordinate appetite and digestion, breathing, and cardiorespiratory reflexes. Using cell‐type‐specific tracing, we show that excitatory Lmx1b neurons project broadly to brainstem and forebrain targets, whereas inhibitory output remains largely brainstem‐restricted. Catecholaminergic (
Silvia Gasparini +5 more
wiley +1 more source
Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
wiley +1 more source
We examined the influence of denoising approaches on diagnostic differences in network topology across the Alzheimer's disease continuum. We show that the directionality of the diagnostic differences in network topology, particularly in global metrics of network segregation, can vary based upon the denoising approach employed.
Jenna K. Blujus +2 more
wiley +1 more source
Salud, juego y comunicación en sectores populares
El objetivo del presente trabajo es dar a conocer una experiencia interdisciplinaria y la sistematización de dos programas universitarios donde se aplica el aprendizaje servicio en relación a la prevención del dengue. La metodología utilizada durante el trabajo de campo es cualitativa y flexible porque no se busca la contrastación empírica sino ...
Abreu, Lucía +4 more
openaire +1 more source
ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source

