Results 161 to 170 of about 460,990 (261)

Machine Learning‐Guided Identification of Madecassoside as a Potential RAD51 Modulator That Sensitizes Breast Cancer Cells to Cisplatin

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Madecassoside was selected from an in‐house natural product library through machine learning‐based virtual screening and identified as a potential modulator of RAD51‐mediated DNA repair that enhances cisplatin sensitivity in breast cancer cells. ABSTRACT Homologous recombination (HR) is an essential pathway for preserving the genomic stability of cells
Minju Oh, Mi‐Young Jeong, Jiwon Choi
wiley   +1 more source

Opportunities and Challenges in Using National EHR Networks for AI in Learning Health Systems. [PDF]

Learn Health Syst
Kukhareva PV, Gouripeddi R, Peek N, Kawamoto K.   +3 more
europepmc   +1 more source

Prevalence, duration, and clinical implications of continuous glucose monitor measurement limit capping in type 1 diabetes

Diabetic Medicine, Volume 43, Issue 10, October 2026.
Abstract Aims CGM devices report glucose only within fixed limits (typically 40–400 mg/dL; 2.2–22.2 mmol/L), truncating extreme values to a boundary (‘capping’). We characterised prevalence, duration, and consequences of capping in type 1 diabetes trial data.
John F. Mulley
wiley   +1 more source

Strengthening human immunodeficiency virus surveillance through systematic data cleaning: a national retrospective validation of the human immunodeficiency virus treatment and care registry in Guyana, 2025. [PDF]

IJID Reg
Jagnarine T, Chalmers M.
europepmc   +1 more source

Early Worsening of Diabetic Retinopathy Following Initiation of Hybrid Closed‐Loop/Automated Insulin Delivery Systems in Type 1 Diabetes: A Systematic Review and Structured Study‐Level Synthesis

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8878-8894, October 2026.
ABSTRACT Background Hybrid closed‐loop (HCL) systems achieve rapid, algorithm‐driven improvements in glycaemia in type 1 diabetes (T1D). Paradoxically, rapid improvement in glycaemic control is associated with early worsening of diabetic retinopathy (EWDR), a phenomenon established in the intensive insulin therapy era.
Matthew Anson, Ahmed Iqbal, Shazli Azmi, Philip Weston, Lucy Hughes, Mahreen Choudhury, David M. Hughes, Yalin Zheng, Philip I. Burgess, Uazman Alam   +9 more
wiley   +1 more source

Geographic and Environmental Differences in Associations Between Food Insecurity and Nutritional and Inflammatory Biomarkers Among Pregnant Participants in the <i>All of Us</i> Research Program. [PDF]

Nutrients
Bashi A, Schuch V, Dawning A, Joseph TT, Baltrus P, Moore CJ, Johnson EL.   +6 more
europepmc   +1 more source

Involving People With Dementia in Research: Contributions, Barriers and Evaluation From a Meta‐Synthesis and Qualitative Interview Study

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Patient and Public Involvement and Engagement (PPIE) can enhance the relevance, acceptability and quality of research; however, its meaningful implementation in dementia research remains insufficiently understood. Aim (1) To identify methodological procedures for involving people with dementia (PwD) across the research lifecycle ...
Jörg Meisser, Susanne de Wolf‐Linder, Christina Ramsenthaler   +2 more
wiley   +1 more source

Design and Implementation of a State-Wide Network for Near Real-Time Public Health Surveillance and Research: The Minnesota Electronic Health Record Consortium Experience. [PDF]

Learn Health Syst
Johnson SG, Chamberlain AM, Drawz P, Dudley RA, Waring SC, Winkelman T, Bodurtha P, Bergmann K, Essien I, Rai NK, Patnoe ST, Margolis KL, MN EHR Consortium.   +12 more
europepmc   +1 more source

Digital Patient Decision Aids for Endometriosis Management: A Scoping Review

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Endometriosis treatment requires women to navigate complex, preference‐sensitive decisions. Patient Decision Aids (PtDAs) help patients make value‐aligned choices. However, the scope and quality of digital PtDAs for endometriosis, and the cap acity of conversational AI platforms to act as PtDAs, remain unclear.
Océane Pittet, Marion Delvallée, Nicola Pluchino, Kevin Selby, Glyn Elwyn, Marie‐Anne Durand   +5 more
wiley   +1 more source

Use of Biometrics for Records Deduplication: Case Study of the National Data Repository in Nigeria. [PDF]

Online J Public Health Inform
Oladipo A, Dalhatu I, Balogun ST, Bamidele M, Fagbemi A, Abbas IA, Nalda N, Ugbena R, Orjih J, Efuntoye TA, Doman B, Patel S, Tolentino H, Rosen D, Kariuki J, Alonge J, Balogun K, Umeh N, Gomez G, Onimode O, Olatoregun O, Samuels JO, Bashorun A.   +22 more
europepmc   +1 more source