Results 61 to 70 of about 18,222,506 (296)
Secure software development practice selection model [PDF]
Developing secure software is critical for organizations as highly-sensitive and confidential data are transacted through online applications. Insecure software can lead to loss of revenue and damage to business reputation.
Kanniah, Sri Lakshmi
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Web development evolution: the business perspective on security [PDF]
Protection of data, information, and knowledge is a hot topic in today’s business environment. Societal, legislative and consumer pressures are forcing companies to examine business strategies, modify processes and acknowledge security to accept and ...
Glisson, L.M. +2 more
core +5 more sources
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Software engineering best practices for developing secure and reliable applications [PDF]
This paper discusses software engineering best practices for developing secure and reliable applications. Presenting a comprehensive overview of the software development process and discuss the importance of incorporating security and reliability into ...
PRODIUS, Cristian
core +1 more source
Software Security and development experts have addressed the problem of building secure software systems. There are several processes and initiatives to achieve secure software systems.
Paulina Silva +5 more
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Automating Risk Analysis of Software Design Models
The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development ...
Maxime Frydman +4 more
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source

