Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Construction of an enterprise-level global supply chain database. [PDF]
Katafuchi Y +5 more
europepmc +1 more source
A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret +6 more
wiley +1 more source
From Nipah virus disease to disease X: Vigilance against the "infodemic". [PDF]
Sun J, Wang G.
europepmc +1 more source
Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato +6 more
wiley +1 more source
Telework and mental health among caregiving workers in Japan: a cross-sectional study using data from the 2024 JACSIS and implications for age-friendly workplaces. [PDF]
Miura T +4 more
europepmc +1 more source
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka +2 more
wiley +1 more source
Changes in body weight, awareness, and behaviors among workers participating in an online specific health guidance program incorporating multiple nudges: a process evaluation. [PDF]
Takebayashi M +4 more
europepmc +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
The evolving landscape of primary headache therapy. [PDF]
Holland PR, Goadsby PJ.
europepmc +1 more source

