Results 151 to 160 of about 2,702,156 (313)
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis
Advanced Science, EarlyView.The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari +20 more
wiley +1 more source
Does agroecosystem management mitigate historic climate impacts on dryland winter wheat yields?
Agronomy Journal, Volume 114, Issue 6, Page 3515-3530, November/December 2022., 2022 Abstract Global studies that quantify climate effects on crop yields using top‐down spatial frameworks are invaluable for assessing generalized effects on world food supplies, yet do not contain the resolution necessary to identify local mediating effects of management. Our objectives were to identify (a) what climate factors have historically affected
Grace L. Miner +6 more
wiley +1 more source
Advanced Science, EarlyView.Assessing species' vulnerabilities across geographical gradients is essential for biodiversity conservation under climate change. To address this challenge, the semi‐natural climate chamber across latitudes (SCCAL) is developed, a validated system capable of simulating thermal environments for ecological experiments without reliance on water or ...
Bao‐Jun Sun +15 more
wiley +1 more source
Yield estimation of summer maize based on multi‐source remote‐sensing data
Agronomy Journal, Volume 114, Issue 6, Page 3389-3406, November/December 2022., 2022 Abstract Accurately estimating regional‐scale crop yields is substantial in determining current agricultural production performance and effective agricultural land management. The Yuncheng Basin is an important grain‐producing area in the Shanxi Province. This paper used Sentinel 2A with a spatial resolution of 10 m and MODIS with a temporal resolution
Jingshu Wang +4 more
wiley +1 more source
Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation
Advanced Science, EarlyView.Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang +9 more
wiley +1 more source
AGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022 The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo +3 more
wiley +1 more source
Advanced Science, EarlyView.A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim +6 more
wiley +1 more source
Do smaller chicken farms use more antibiotics? Evidence of antibiotic diffusion from Nigeria
Agribusiness, Volume 39, Issue 1, Page 242-262, Winter 2023., 2023 Abstract Farmers across the world have been using antibiotics in poultry production for both therapeutic and nontherapeutic purposes since the mid 1900s. The literature on antibiotic diffusion and intensification is largely focused on developed countries in North America and Western Europe.
Charuta M. Parkhi +2 more
wiley +1 more source