Results 41 to 50 of about 2,449,057 (299)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Determinants of Profitability Among Agricultural Equipment Fabricators in Oyo State, Nigeria

open access: yesJournal of Agricultural Extension
The study examined enterprise profitability among agricultural equipment fabricators. It was conducted in Oyo State, Nigeria using a multistage sampling procedure to select the 48 respondents from whom data were collected using a structured questionnaire.
Oyelami, Benjamin Olusegun   +8 more
doaj   +1 more source

Towards alignment of architectural domains in security policy specifications [PDF]

open access: yes, 2006
Large organizations need to align the security architecture across three different domains: access control, network layout and physical infrastructure.
Franqueira, Virginia Nunes Leal   +1 more
core   +5 more sources

The Application of AHP Model to Guide Decision Makers: A Case Study of E-banking Security

open access: yes, 2009
Changes in technology have resulted in new ways for bankers to deliver their services to costumers. Electronic banking systems in various forms are the evidence of such advancement.
Hwang, Junseok, Syamsuddin, Irfan
core   +1 more source

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper   +7 more
wiley   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

The climate and ocean risk vulnerability index: Measuring coastal city resilience to inform action

open access: yesFrontiers in Sustainable Cities, 2022
Today, coastal cities worldwide are struggling with the complex interaction of environmental threats, economic development, and societal inequity. The acceleration of global climate change, which will impact ocean health, sea level, rainfall patterns ...
Tracy Rouleau   +6 more
doaj   +1 more source

Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics

open access: yesAdvanced Functional Materials, EarlyView.
Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha   +15 more
wiley   +1 more source

A New Fuzzy MCDM Framework to Evaluate E-Government Security Strategy

open access: yes, 2010
Ensuring security of e-government applications and infrastructures is crucial to maintain trust among stakeholders to store, process and exchange information over the e-government systems. Due to dynamic and continuous threats on e-government information
Hwang, Junseok, Syamsuddin, Irfan
core   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

open access: yesAdvanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee   +21 more
wiley   +1 more source

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