Results 181 to 190 of about 2,383,360 (354)

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

SECURE SERVICE PUBLISHING WITH UNTRUSTED REGISTRIES - Securing Service Discovery

Proceedings of the Second International Conference on Security and Cryptography, 2007
openaire   +3 more sources

Editorial: Advanced intelligent and security services in mobile and ubiquitous computing [PDF]

, 2010
Ilsun You, Witold Pedrycz
openalex   +1 more source

A Constructive DIREST Security Threat Modeling for Drone as a Service

, 2021
Fahad E. Salamh, Ümit Karabiyik, Marcus Rogers   +2 more
openalex   +2 more sources

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

INSTITUTIONAL ENVIRONMENT OF DEVELOPMENT OF SERVICES IN COMMUNITIES AS A FACTOR OF FOOD AND SOCIAL SECURITY [PDF]

Iryna Honcharenko, I.V. Moskal
openalex   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

The Sense of Security and Associated Factors Among Older Home Care Clients: A Register Study. [PDF]

Scand J Caring Sci
Mira P, Turja T, Mari A, Johanna E, Marja K.   +4 more
europepmc   +1 more source

Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”

Advanced Science, EarlyView.
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner, Nina Claessens, Caitlin M. Maloney, Peter Claes   +3 more
wiley   +1 more source

Affordability of Water Service from Perspective of Water Security of Community in Bekasi District

, 2019
Ninin Gusdini, M. Anis Januar, Joko Purwanto, Kukuh Murtilaksono   +3 more
openalex   +2 more sources