Results 201 to 210 of about 175,201 (271)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

SEDATION FOR ENDOSCOPY: MIDAZOLAM OR DIAZEPAM AND PETHIDINE?

, 1988
D.A.R. Boldy, L.R. Lever, P.R. UNWIN, Paulette Spencer, A M Hoare   +4 more
openalex   +1 more source

Use of sedative drugs in specialist palliative care (iSedPall): a multi-modal intervention pilot study protocol. [PDF]

Pilot Feasibility Stud
Ostgathe C, Bausewein C, Schildmann E, Bazata J, Heckel M, Kauzner S, Klein C, Krauss SH, Kremling A, Schneider M, Seifert A, Ziegler K, Jäger C, Schildmann J.   +13 more
europepmc   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

SEDATION AND RESPIRATORY MECHANICS IN MAN

, 1983
Adrian W. Gelb, Peter A. Southorn, Edward P. Didier, Kai Rehder   +3 more
openalex   +1 more source

Alfentanil and fentanyl sedation in infants and small children during cardiac catheterization [PDF]

, 1990
Olli A. Meretoja, Paula Rautiainen
openalex   +1 more source

Isoflurane vs. Propofol Sedation in Patients with Severe Stroke: A Clinical Proof-of-Concept-Study. [PDF]

J Clin Med
Worm A, Claudi C, Braun SR, Schenker M, Meyer A, Moeller L, Simon OJ, Timmermann L, Mrochen A, Diel NJ, Juenemann M, Huttner HB, Schramm P.   +12 more
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Anesthesia and Sedation in the Dental Office

, 1986
Sanford L. Klein
openalex   +1 more source

A comparison of morphine-perphenazine and midazolam on preoperative sedation and arterial oxygen saturation [PDF]

, 1991
Elliot T. Hudes, Howard J. Marans, Kevin Shine, Andrew C. Scott, Gail M. Hirano   +4 more
openalex   +1 more source