Results 41 to 50 of about 178,193 (264)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Dento–Osseous Variability of the Mental Foramen: A Retrospective CT-Based Morphometric Study

Medicina
Background and Objectives: This study aimed to identify osseous and dental mandibular landmarks that consistently indicate the location of the mental foramen, the primary reference for the mental–incisive trunk block.
Andrei Urîtu, Alexandra Roi, Ciprian Roi, Doina Chioran, Alexandru Cătălin Motofelea, Ioana Riviș, Mircea-Alexandru Bălășoiu, Radu Dan, Mircea Riviș   +8 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Alteration of coupling between brain and heart induced by sedation with propofol and midazolam.

PLoS ONE, 2019
For a comprehensive understanding of the nervous system, several previous studies have examined the network connections between the brain and the heart in diverse conditions. In this study, we identified coupling between the brain and the heart along the
Dong-Ok Won, Bo-Ram Lee, Kwang-Suk Seo, Hyun Jeong Kim, Seong-Whan Lee   +4 more
doaj   +1 more source

Korean clinical practice guidelines for diagnostic and procedural sedation [PDF]

Korean Journal of Anesthesiology
Safe and effective sedation depends on various factors, such as the choice of sedatives, sedation techniques used, experience of the sedation provider, degree of sedation-related education and training, equipment and healthcare worker availability, the ...
Sang-Hyun Kim, Young-Jin Moon, Min Suk Chae, Yea-Ji Lee, Myong-Hwan Karm, Eun-Young Joo, Jeong-Jin Min, Bon-Nyeo Koo, Jeong-Hyun Choi, Jin-Young Hwang, Yeonmi Yang, Min A Kwon, Hyun Jung Koh, Jong Yeop Kim, Sun Young Park, Hyunjee Kim, Yang-Hoon Chung, Na Young Kim, Sung Uk Choi   +18 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Current sedation practices for non-invasive procedures in tertiary maternity and children’s hospitals in China: a 5-year update

BMJ Paediatrics Open
Background Sedation techniques can ease anxiety during medical procedures for children. Our previous report on Chinese sedation practices for non-invasive procedures in 2018 is outdated due to the rapid development of sedation services.
Lu Wang, Bo Li, Ruidong Zhang, Yanhui Huang, Mazhong Zhang, Jijian Zheng   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Procedural Sedation and Analgesia in Children: Perspectives from Paediatric Emergency Physicians

Proceedings of Singapore Healthcare, 2010
Procedural sedation and analgesia in children is now widely practised in many emergency departments internationally. In this article, we address the general principles, indications, guidelines, medications, adverse events and future research in ...
Lai Peng Tham MBBS, MMed (Paediatrics), Khai Pin Lee M.Med (Paediatrics) MRCPCH   +1 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source