Results 121 to 130 of about 68,013 (302)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A case report of pediatric ketamine sedation: An unexpected turn of events

JEM Reports
Background: Ketamine is an agent commonly used for procedural sedation and anesthesia during pediatric fracture reductions in the emergency department. It is popular for its rapid onset, favorable safety profile and ease of monitoring, with most adverse ...
Gabriella Taylor, Alyssa Gill, Amelia Kruse   +2 more
doaj   +1 more source

Management of paediatric procedure-related cancer pain

, 1999
Paediatric malignancy is not always painful in its own right; however, young patients with cancer undergo numerous painful procedures for diagnosis, therapy and supportive care, including lumbar puncture, bone marrow aspiration and biopsy.
Liossi, C.
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Impact of propofol infusion-based sedation on anesthesia-related adverse events in endoscopic ultrasonography: A prospective observational study

Medicine Science
Procedural sedation is recommended for endoscopic ultrasonography (EUS) to enhance patient comfort and optimize procedural conditions. This study aimed to evaluate the impact of continuous propofol infusion as the main component of the sedation protocol ...
Caner Genc, Nevzat Gumus, Ahmet Ozan Aydin, Hatice Kusderci, Kasim Demir, Taner Akyol, Umut Emre Aykut, Ozgur Komurcu   +7 more
doaj   +1 more source

Evaluation of the compliance between EEG monitoring (Bispectral Index (TM)) and Ramsey Sedation Scale to measure the death of sedation in the patients who underwent procedural sedation and analgesia in the emergency department

, 2019
BACKGROUND: This study aimed to investigate the compliance between electroencephalogram monitoring (Bispectral Index, BIS) and Ramsay Sedation Scale (RSS) to measure the depth of sedation in patients who underwent procedural sedation and analgesia (PSA ...
BAYRAM, BAŞAK, Inanc, Gonca, Oniz, Adile, Ozgoren, Murat, ÇOLAK, NEŞE, Goren, Nurfer, Avci, Sinem   +6 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Evaluation of deep sedation effects and respiratory aspects of remimazolam besylate in elderly patients undergoing fiberoptic bronchoscopy

Frontiers in Medicine
BackgroundThe geriatric population, especially individuals over 65 years old with comorbidities classified by the ASA (American Society of Anesthesiologists) grading system, requires careful sedation management during flexible bronchoscopy (FB) to reduce
Dongmei Ma, Li Li, Fuyi Han, Jianhong Xu, Cheng Zhang   +4 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Additional file 3: of Monitoring of sedation depth in intensive care unit by therapeutic drug monitoring? A prospective observation study of medical intensive care patients

, 2018
Monitoring the depth of sedation with BIS-monitoring [12].
Richard Nies (5749985), Philipp Binder (5749988), Martin Wiesen (469778), Felix Nettersheim (5749994), Carsten MĂźller (5750030), Roman Pfister (199354), Nicole Nosseir (5749991), Kathrin Kuhr (334603), Guido Michels (378142), Matthias Kochanek (3092526)   +9 more
core   +1 more source