Results 211 to 220 of about 472,347 (311)

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

Cancer Science, EarlyView.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng, You Zhou, Sijie Song, Hongtao Liu, Siqi Liao, Li Zhou, Siyuan Chen, Zhihang Zhou, Song He, Bingrong Liu   +9 more
wiley   +1 more source

The Mediating Role of Screen-Based Sedentary Behaviors in the Association of Parental Educational Level and BMI with Preschoolers' Ultra-Processed Food Consumption. [PDF]

Nutrients
Machado-Rodrigues AM, Fernandes HM, Stabelini Neto A, Dos Santos EA, Tur JA, Padez C, Rodrigues D.   +6 more
europepmc   +1 more source

Sarcopenia and its association with physical activity and sedentary time in older adults on the Bushehr Elderly Health program. [PDF]

Sci Rep
Farhadi A, Mohammadian M, Afrashteh S, Jorjani G, Mousavi S, Nabipour I, Larijani B.   +6 more
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

The need for trained graduates to promote exercise as a mode of preventative healthcare in the United Arab Emirates

Frontiers in Sports and Active Living
Paul Stapley, Jean-Pierre Bailey, Khalil Yousef, Khalil Yousef, Romuald Lepers, Suzanne Robertson-Malt, Suzanne Robertson-Malt   +6 more
doaj   +1 more source

Metabolite biomarkers present in urine predict alterations in skeletal muscle associated with sarcopenia. [PDF]

Front Aging
Andrade-Vieira R, Feridooni HA, Teixeira A, Deska-Gauthier D, Chang X, Karakach T, Moyer R, Frampton JP.   +7 more
europepmc   +1 more source

Demographic Predictors Associated With Elevated Screen Use in Preschoolers: A Multinational Cross‐Sectional Study Based on Parents' Reports

Child &Family Social Work, EarlyView.
ABSTRACT The widespread use of smartphones and tablets has greatly increased screen exposure among preschoolers. Since early childhood is crucial for cognitive, behavioural and social development, excessive screen time represents a major public health concern.
Neha Pirwani, Róbert Járai, Robert Podstawski, Ricardo de la Vega, Celal Bulgay, Attila Szabo   +5 more
wiley   +1 more source

Interaction effects of sedentary behavior and depression on MAFLD in NHANES 2017-2020 and 2021-2023. [PDF]

PLoS One
Zhang W, Wang Y, Cong Q, Tang X, Wang Z, Wang Z.   +5 more
europepmc   +1 more source

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet, Iain K. Robertson, Sharon P. Luccisano, Michelle L. Kilpatrick   +3 more
wiley   +1 more source