Results 201 to 210 of about 93,220 (267)

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Sedentary Behavior and Low Back Pain in Children and Adolescents: A Systematic Review and Meta-Analysis. [PDF]

Healthcare (Basel)
Calvo-Muñoz I, García-Moreno JM, Gómez-Conesa A, López-López JA.   +3 more
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Association of park features with total and prolonged sedentary behavior among older adults: An observational study in Macau. [PDF]

Sci Rep
Chen Y, Zheng J, Huang L.
europepmc   +1 more source

Demographic Predictors Associated With Elevated Screen Use in Preschoolers: A Multinational Cross‐Sectional Study Based on Parents' Reports

Child &Family Social Work, EarlyView.
ABSTRACT The widespread use of smartphones and tablets has greatly increased screen exposure among preschoolers. Since early childhood is crucial for cognitive, behavioural and social development, excessive screen time represents a major public health concern.
Neha Pirwani, Róbert Járai, Robert Podstawski, Ricardo de la Vega, Celal Bulgay, Attila Szabo   +5 more
wiley   +1 more source

Reducing sedentary behavior through workplace counseling: effects on activity, sitting breaks, and well-being - a randomized controlled trial. [PDF]

Arch Public Health
Engeroff T, Kraus L, Wilke J, Niederer D, Groneberg D.   +4 more
europepmc   +1 more source

‘It Is More Fun to Try It Out for Yourself’: Lower Secondary School Pupils' Perceptions of Physically Active Learning

Children &Society, EarlyView.
ABSTRACT This article explores lower secondary school pupils' perceptions of physically active learning (PAL). Specifically, we explore what educational purposes 12 Norwegian 9th graders perceive PAL contributes to. Five lessons with PAL were observed and informed three subsequent focus groups.
Hege Eikeland Tjomsland, Vigdis Stokker, Anette Teigland Kråkenes, Helga Bjørnøy Urke, Mathias Brekke Mandelid   +4 more
wiley   +1 more source

Acute effects of physical activity breaking up sedentary behavior on cognitive function, biological mechanisms, and practical recommendations: a systematic review. [PDF]

Front Psychol
Li Y, Jiang Y, Yin X, Song Y, Yao N, Shen Z, Chen Q.   +6 more
europepmc   +1 more source

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet, Iain K. Robertson, Sharon P. Luccisano, Michelle L. Kilpatrick   +3 more
wiley   +1 more source

Sedentary behavior, physical activity, psychological well-being, and gynecologic and obstetric disorders: A multivariable Mendelian randomization and mediation analysis. [PDF]

Medicine (Baltimore)
Hu Y, Cao Y, Wu H, Wang B, Li J, Xia W, Zhan B.   +6 more
europepmc   +1 more source