Results 251 to 260 of about 6,523,385 (358)

Sedentary Behavior and Low Back Pain in Children and Adolescents: A Systematic Review and Meta-Analysis. [PDF]

open access: yesHealthcare (Basel)
Calvo-Muñoz I   +3 more
europepmc   +1 more source

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

open access: yesCancer Science, EarlyView.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng   +9 more
wiley   +1 more source

Sedentary behavior and mental health assessment in advanced stage cancer patients. [PDF]

open access: yesAten Primaria
Sepulveda H   +3 more
europepmc   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth   +7 more
wiley   +1 more source

Frailty in Chinese older adults: the roles of sedentary behavior, relative sit-to-stand power, and their additive interaction. [PDF]

open access: yesBMC Geriatr
Jiarong Z   +8 more
europepmc   +1 more source

Demographic Predictors Associated With Elevated Screen Use in Preschoolers: A Multinational Cross‐Sectional Study Based on Parents' Reports

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT The widespread use of smartphones and tablets has greatly increased screen exposure among preschoolers. Since early childhood is crucial for cognitive, behavioural and social development, excessive screen time represents a major public health concern.
Neha Pirwani   +5 more
wiley   +1 more source

Associations of sedentary behavior and physical activity with sleep disorders in patients with osteoarthritis: The mediating role of inflammatory biomarkers. [PDF]

open access: yesOsteoarthr Cartil Open
Luo B   +11 more
europepmc   +1 more source

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet   +3 more
wiley   +1 more source

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