Results 141 to 150 of about 2,057,948 (291)

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

Medicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang, Wen‐Bi He, Fei‐Peng Chen, Jiong‐Xing Huang, Lin Zhu, Xiao‐Guang Liu   +5 more
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Fatigue in Myasthenia Gravis: Recent Advances and Emerging Concepts

Muscle &Nerve, EarlyView.
ABSTRACT Fatigue is a common, often disabling symptom in myasthenia gravis (MG), distinct from muscle fatigability, and strongly associated with reduced quality of life. This narrative review examines current evidence on fatigue in MG, its patient impact, and future research directions. Earlier studies, mostly small and heterogeneous, reported a highly
Yvonne J. M. Campman, Martijn R. Tannemaat, Annabel M. Ruiter, Sarah Hoffmann   +3 more
wiley   +1 more source

Impact of Dietetic Counseling Combined With Digital Tools on Obesity‐Related Indices in Greek Adults: The GATEKEEPER Study

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the effectiveness of dietetic counseling with digital tools on obesity‐related and metabolic outcomes in adults aged ≥ 55 years at high risk for metabolic syndrome (MetS). Methods In this 3‐month randomized controlled trial, 984 adults aged ≥ 55 years with ≥ 1 MetS risk factor were randomized (1:1:1) to ...
Rafaela Makri, Iliana Evangelou, Eva Karaglani, Maria Vlachava, George E. Dafoulas, Ioanna Drympeta, Konstantinos Votis, Eleni I. Georga, Dimitrios I. Fotiadis, Francisco Lupiáñez‐Villanueva, Frans Folkvord, Leandro Pecchia, Giuseppe Fico, Demosthenes Panagiotakos, Odysseas Androutsos, Yannis Manios, GATEKEEPER study (Greek Use Case 1) group, Odysseas Androutsos, Maria Vlachava, Iliana Evangelou, George E. Dafoulas, Alexandra Bargiota, Alexandra Koubitski, Avgi Karaiskou, Glykeria Papagiannopoulou, Thanasis Topis, Thomas Tzekos, Nelly Mylona, Nikos Papaspanos, Yvonne Katergari, Iphigenia Chionidou, Natasha Davitidou, Vivian Katsarou, Yannis Manios, Eva Karaglani, Rafaela Makri, Ilektra Kalogerakou, Alexandros Karagiannis, Ioanna Nakaki, Elpiniki Vlachopoulou, Maria Dimopoulou, Maria Skaltsa, Ioannis Chrysou, Konstantinos Leontiou, Karamperi Katerina, Evangelia Malakou, Anastasios Papalazarou, Elisavet Parlapani, Anastasia Paschaleri, Christos Paximadas, Maria‐Sofia Pelagidou, Kyriakos Reppas, Katerina Tyrothoulaki, Konstantinos Xenos, Spyridon Zarogiannis, Konstantinos Zervos, Ilias Kalamaras, Dimitrios I. Fotiadis, Eleni I. Georga, Daphne N. Katsarou   +59 more
wiley   +1 more source

The economic costs of excessive sedentary behaviour in Japan. [PDF]

J Public Health (Oxf)
Mitsutake S, Shibata A, Ishii K, Owen N, Oka K.   +4 more
europepmc   +1 more source

Sedentary Behaviour and Obesity: Review of the Current Scientific Evidence

, 2010
1. Sedentary behaviour is not simply a lack of physical activity but is a cluster of individual behaviours where sitting or lying is the dominant mode of posture and energy expenditure is very low. 2.
Prosser, L, Cavill, N, Ekelund, U, Griffiths, M, Vicente-Rodríguez, G, Butland, B, Stratton, G, Biddle, S, Jago, R, Raats, MM, The Sedentary Behaviour and Obesity Expert Working Group,, Salmon, J, Oppert, JM, Gorely, T, Richardson, D   +14 more
core  

Trends of Obesity in Early Adulthood and Later Adulthood Across 196 Countries and Territories, 1990–2022

Obesity, EarlyView.
ABSTRACT Objective We aimed to understand the global burden of obesity in early adulthood and later adulthood over the past three decades. Methods We analyzed obesity prevalence across 196 countries/territories from 1990 to 2022 for early adulthood (age 20–49 years) and later adulthood (age ≥ 50 years) using the Non‐Communicable Disease Risk Factor ...
Abdiwahab M. Ali, Edward Giovannucci, Jason J. Liu   +2 more
wiley   +1 more source

Physical Activity-Sedentary Behaviour Profiles and Associated Lifestyle Characteristics in Adolescents: A Cross-Sectional Study. [PDF]

Nutrients
Wojciechowska M, Cieśla E, Żurawski AŁ, Zmyślna A, Kozieł D.   +4 more
europepmc   +1 more source

Weight Loss Improves Predicted 10‐Year MACE and Type 2 Diabetes Risk, but Benefits Partially Rebound at 1 Year

Obesity, EarlyView.
ABSTRACT Objective This study aimed to quantify changes in predicted 10‐year risk for major adverse cardiovascular events (MACE) and type 2 diabetes (T2D) across weight loss, post–weight loss (Post‐WL), and 1‐year follow‐up and to determine whether trajectories varied by exercise modality.
Abdelrahman M. Elshakankiry, Gary R. Hunter, Cátia Martins, Gordon Fisher, W. Timothy Garvey, Carrie R. Howell   +5 more
wiley   +1 more source

Physical Activity-Sedentary Behaviour Profiles and Co-Occurring Lifestyle Behaviours Among Adolescents: A Person-Oriented Analysis. [PDF]

Nutrients
Wojciechowska M, Żurawski AŁ, Cieśla E, Zmyślna A, Kozieł D.   +4 more
europepmc   +1 more source