Results 231 to 240 of about 31,280 (312)

Physical Activity, Sleep and Sedentary Behaviour of Adults With Intellectual Disabilities, Family Caregivers and Service Providers During COVID‐19 Pandemic Recovery

British Journal of Learning Disabilities, EarlyView.
ABSTRACT Background Guidelines outline recommended amounts of physical activity (PA), sleep and sedentary time for optimal health. Research suggests that adults with intellectual disabilities (ID) often do not meet recommendations and that engagement in healthy behaviours is impacted by those around them. The COVID‐19 pandemic amplified these concerns.
Laura C. Koch, Yona Lunsky, Kathleen Tremells, Tiziana Volpe, Anupam Thakur, Johanna Lake, Laura St. John   +6 more
wiley   +1 more source

Study protocol for a feasibility randomised controlled trial of MOVE SMART-An intervention to increase physical activity, reduce sedentary behaviour and improve health outcomes in patients with psoriasis. [PDF]

PLoS One
Onambele-Pearson G, Ives B, Khosla I, Witkam R, Roberts M, Moorhead L, Bedson E, Cowper R, Burnside G, Young HS.   +9 more
europepmc   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Sedentary behaviour and activity patterns of older adults in an acute hospital setting: An exploratory study. [PDF]

Br J Occup Ther
Brown LJ, Warne SJ, Liu CN, Hutchins J, McVeigh J, Thompson C, Harper KJ.   +6 more
europepmc   +1 more source

Physical activity and sedentary behaviour interventions for people living with both frailty and multiple long-term conditions and their informal carers: a scoping review and stakeholder consultation [PDF]

Hannah Young, Joseph Henson, Paddy C. Dempsey, Scott A. Willis, Roseanne E Billany, Ffion Curtis, Laura J. Gray, Sharlene A. Greenwood, Louisa Herring, Patrick J. Highton, Ryan Kelsey, Selina Lock, Daniel S. March, Krishna Patel, Jack A. Sargeant, Harini Sathanapally, Avan Aihie Sayer, Martha Thomas, Noemi Vadaszy, Emma C. Watson, Tom Yates, Melanie J. Davies   +21 more
openalex   +1 more source

Pharmacological activation of NO‐cGMP signalling attenuates metabolic dysfunction‐associated steatohepatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Metabolic dysfunction‐associated steatohepatitis (MASH) is linked to activation of hepatic stellate cells (HSCs) to α‐smooth muscle actin–positive myofibroblasts that produce collagen and proinflammatory cytokines. Quiescent HSCs express the NO‐cGMP signalling axis.
Krithika Rajeeth, Malte Roessing, Moritz Lehners, Lisa Dietz, Anja Schmitt, Stephan Hailfinger, Andreas Peter, Leticia Quintanilla‐Martinez, Irene Gonzalez‐Menendez, Ingmar Mederacke, German Ott, Peter Sandner, Matthias Schwab, Robert Feil, Susanne Feil   +14 more
wiley   +1 more source

Effects of reducing sedentary behaviour on cardiovascular health, skeletal muscle oxidative capacity and functional exercise capacity in sedentary adults: a randomised controlled trial. [PDF]

BMJ Open Sport Exerc Med
Franssen WMA, Nieste I, Koppo K, Joris P, Vandereyt F, Savelberg HHCM, Eijnde BO.   +6 more
europepmc   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Do physical activity and sedentary behaviour have an effect on burnout risk in Flemish secondary school teachers? A prospective study. [PDF]

BMC Public Health
Verhavert Y, Van Hoof E, Van Cauwenberg J, de Vries J, Clarys P, Zinzen E, De Martelaer K, Deliens T.   +7 more
europepmc   +1 more source