Results 61 to 70 of about 31,280 (312)

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

Sedentary behaviour may cause differences in physical outcomes and activities of daily living in older cardiovascular disease patients participating in phase I cardiac rehabilitation

Scientific Reports
This study aimed to investigate the rate of sedentary behaviour and differences in physical outcomes and activities of daily living (ADL) based on sedentary behaviour time of hospitalized older cardiovascular disease patients undergoing phase I cardiac ...
Kazuhiro P. Izawa, Kodai Ishihara, Yuji Kanejima, Masahiro Kitamura, Asami Ogura, Ikko Kubo, Koichiro Oka, Peter H. Brubaker, Hitomi Nagashima, Hideto Tawa, Daisuke Matsumoto, Ikki Shimizu   +11 more
doaj   +1 more source

The association between sedentary behaviour and sarcopenia in older adults: a systematic review and meta-analysis

BMC Geriatrics, 2023
Background Sedentary behaviour is considered to contribute to sarcopenia when combined with physical inactivity. Whether sedentary behaviour is independently associated with sarcopenia remains controversial.
Yihan Mo, Yuxin Zhou, Helen Chan, Catherine Evans, Matthew Maddocks   +4 more
doaj   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Interventions to reduce sedentary behaviour in adults with type 2 diabetes: A systematic review and meta-analysis.

PLoS ONE
Treatment and management of Type 2 Diabetes (T2D) includes physical activity, nutrition, and pharmacological management. Recently, the importance of reducing and breaking up sedentary behaviour has become recognized.
Siobhan Smith, Babac Salmani, Jordan LeSarge, Kirsten Dillon-Rossiter, Anisa Morava, Harry Prapavessis   +5 more
doaj   +1 more source

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source

The 9+ month marathon: How pregnancy may have shaped human endurance capacities

The Anatomical Record, EarlyView.
Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley   +1 more source

Parents’ perceptions of their children’s sedentary behaviour [PDF]

Qualitative Research in Sport, Exercise and Health, 2015
Sedentary behaviour is complex, occurring in different contexts and influenced by numerous factors. One such context is the home environment where the family setting can determine the type and amount of sedentary behaviour that occurs. There is limited evidence examining sedentary behaviours within a family setting, specifically in children aged 2–11 ...
Knowles, Ann-Marie, Kirk, Alison F., Hughes, Adrienne R.   +2 more
openaire   +3 more sources

Sleep‐trackers in the wild: A faceted taxonomy for information and interaction design

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Consumer‐grade sleep‐tracking technologies (CSTs) have brought sleep into everyday data practices, reframing it from a clinical concern into a site of personal optimization and reflection. Yet existing taxonomies of sleep‐tracking often medicalize users and overlook the complexity of sleep‐tracking technologies. This paper presents SleepTax, a
Sanonda Datta Gupta, Jaime Snyder, John S. Seberger   +2 more
wiley   +1 more source

Motor Disorders in Autism: From Comorbidity to Core Criterion

Autism Research, EarlyView.
ABSTRACT While repetitive movements are recognized as a diagnostic hallmark of Autism Spectrum Disorder (ASD) in frameworks such as the DSM and ICD, other motor disturbances, including gait atypicalities and postural control difficulties, have historically been overlooked or framed as secondary comorbidities.
Mohamed Jaber
wiley   +1 more source