Results 61 to 70 of about 2,057,948 (291)

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Sedentary behaviour may cause differences in physical outcomes and activities of daily living in older cardiovascular disease patients participating in phase I cardiac rehabilitation

Scientific Reports
This study aimed to investigate the rate of sedentary behaviour and differences in physical outcomes and activities of daily living (ADL) based on sedentary behaviour time of hospitalized older cardiovascular disease patients undergoing phase I cardiac ...
Kazuhiro P. Izawa, Kodai Ishihara, Yuji Kanejima, Masahiro Kitamura, Asami Ogura, Ikko Kubo, Koichiro Oka, Peter H. Brubaker, Hitomi Nagashima, Hideto Tawa, Daisuke Matsumoto, Ikki Shimizu   +11 more
doaj   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Comparison of accelerometry cut points for physical activity and sedentary behavior in pre-school children : a validation study [PDF]

, 2012
This study compared accelerometry cut points for sedentary behavior, light and moderate to vigorous intensity activity (MVPA) against a criterion measure, the Children’s Activity Rating Scale (CARS), in preschool children.
Reilly, J. J., Bulley, Catherine, Mercer, Tom, Bulley, Cathy, Hislop, Jane, Hislop, Jane F., Reilly, John J., Hislop, J., Mercer, Tom H., Reilly, John, Reilly, J J   +10 more
core   +4 more sources

Market‐Based Nutrition Regulation and Adult BMI Dynamics in Latin America

Agribusiness, EarlyView.
ABSTRACT Market‐based nutrition policies, including interpretative labeling systems and taxes on sugar‐sweetened beverages (SSBs), have been widely adopted across Latin America to influence dietary choices and address rising obesity rates. While prior research documents change in food purchasing and product reformulation following these policies ...
Emiliano Lopez Barrera, Grace Melo
wiley   +1 more source

Interventions to reduce sedentary behaviour in adults with type 2 diabetes: A systematic review and meta-analysis.

PLoS ONE
Treatment and management of Type 2 Diabetes (T2D) includes physical activity, nutrition, and pharmacological management. Recently, the importance of reducing and breaking up sedentary behaviour has become recognized.
Siobhan Smith, Babac Salmani, Jordan LeSarge, Kirsten Dillon-Rossiter, Anisa Morava, Harry Prapavessis   +5 more
doaj   +1 more source

Interventions reducing sedentary behaviour of adults: An update of evidence

, 2019
Objectives: This review updates evidence of previous reviews on interventions that target reducing sedentary behaviour among 18- to 69-year-old working aged adults.
Sutherland, Casey A., Kynn, Mary, Gray, Marion A., Cole, Rachel L.   +3 more
core   +1 more source

Interventions to improve exercise behaviour in sedentary people living with and beyond cancer: a systematic review. [PDF]

, 2014
To systematically review the effects of interventions to improve exercise behaviour in sedentary people living with and beyond ...
Thaha, MA, Steed, L., K A Robb, Homer, Kate, Thaha, M.A., Rosario, DJ, Bourke, Liam, Robb, Karen, Robb, KA, M A Thaha, Saxton, John, Taylor, SJ, Taylor, S.J.C., S J C Taylor, Steed, Liz, Saxton, J.M., D J Rosario, Rosario, D.J., Robb, K.A., K E Homer, J M Saxton, Saxton, JM, Taylor, Stephanie, L Bourke, Bourke, L, Thaha, Mohamed, Rosario, Derek J., L Steed, Homer, K.E., Taylor, SJC, Homer, KE, Steed, L, Bourke, L.   +32 more
core   +1 more source

Return‐To‐Work and Working Status After Surgery for Gastric and Esophageal Cancer: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter prospective study of 158 working‐age patients undergoing curative‐intent surgery for gastric or esophageal cancer, 78.5% were working at 18 months. Postoperative appetite loss, financial difficulties, and ≥ 10% weight loss at 6 months were associated with non‐working status.
Kentaro Goto, Shigeo Hisamori, Kohei Ueno, Hiroyasu Abe, Ryosuke Okamura, Hisahiro Hosogi, Yoshito Yamashita, Dai Manaka, Hiroaki Hata, Tatsuto Nishigori, Sanae Nakajima, Michihiro Yamamoto, Koichi Kinoshita, Shintaro Okumura, Masazumi Sakaguchi, Shigeru Tsunoda, Yu Sakagami, Koya Hida, Kazutaka Obama   +18 more
wiley   +1 more source

Sedentary behaviour and adiposity in youth: a systematic review of reviews and analysis of causality

International Journal of Behavioral Nutrition and Physical Activity, 2017
Background Sedentary behaviour (sitting time) has becoming a very popular topic for research and translation since early studies on TV viewing in children in the 1980s.
Stuart J.H. Biddle, Enrique García Bengoechea, Glen Wiesner   +2 more
doaj   +1 more source