Results 201 to 210 of about 95,792 (263)
Experimental Physiology, EarlyView.Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller +2 more
wiley +1 more source
The therapeutic role of exercise training during menopause for reducing vascular disease
Experimental Physiology, EarlyView.Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing +4 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Knee osteoarthritis is experienced by hundreds of millions of people worldwide and is a major cause of disability. Although enhancing physical activity levels and the participation in exercise programmes has been proved to improve the debilitating illness of osteoarthritis, many do not engage in recommended levels of physical activity.
Karl Morgan +3 more
wiley +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Experimental Physiology, EarlyView.Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Muscle disuse leads to muscle atrophy and a decrease in muscle function that is primarily driven by reduced muscle protein synthesis (MPS). The aim of this systematic review and meta‐analysis was to examine the effect of different models of muscle disuse on rates of MPS.
Konstantinos Prokopidis +4 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir +5 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract The objective of this work was to examine whether leg‐fidgeting breaks during prolonged sitting could be a practical alternative to standing breaks in preventing blood pressure (BP) and heart rate (HR) impairments. Young women (n = 16; age = 21.9 ± 3.0 years; body mass index = 21.1 ± 4.9 kg/m2) completed three 3‐h prolonged sitting conditions ...
Saja Alghamdi +4 more
wiley +1 more source