Results 71 to 80 of about 95,792 (263)

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

Obesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand, Camille Le Cudennec, Estelle Grasset, Natalia Breyner, Claire Bigot, Pierre Dillard, Thierry Sulpice   +6 more
wiley   +1 more source

Mutual associations between self‐efficacy and physical fitness in Spanish adolescents: The EHDLA study

Pediatric Investigation, EarlyView.
This study reveals a bidirectional association between self‐efficacy and various components of physical fitness, specifically cardiorespiratory fitness, lower body muscular fitness, and speed‐agility, in Spanish adolescents. Higher physical fitness levels predicted greater self‐efficacy, and conversely, higher self‐efficacy predicted physical fitness ...
José Adrián Montenegro‐Espinosa, Pablo Galan‐Lopez, Rodrigo Yañéz‐Sepúlveda, Héctor Gutiérrez‐Espinoza, Jorge Olivares‐Arancibia, Samuel Manzano‐Carrasco, Masoud Rahmati, Brendon Stubbs, Lee Smith, José Francisco López‐Gil   +9 more
wiley   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors

Preventive Medicine Reports, 2016
Sedentary behavior (sitting/lying at low energy expenditure while awake) is emerging as an important risk factor that may compromise the health-related quality of life (HRQoL) of colorectal cancer (CRC) survivors.
Eline H. van Roekel, Elisabeth A.H. Winkler, Martijn J.L. Bours, Brigid M. Lynch, Paul J.B. Willems, Kenneth Meijer, IJmert Kant, Geerard L. Beets, Silvia Sanduleanu, Genevieve N. Healy, Matty P. Weijenberg   +10 more
doaj   +1 more source

General and central obesities were associated with increased risk of inflammatory bowel disease: A large‐scale prospective cohort study

VIEW, EarlyView.
Prior evidence suggested inconsistent findings in terms of the relationship between obesity and inflammatory bowel disease (IBD) occurrence. We demonstrated that both general and central obesities were associated with an increased risk of developing IBD, ulcerative colitis, and Crohn's disease in a large‐scale prospective cohort.
Qian Zhang, Yijun Chen, Shuang Yu, Si Liu, Shutian Zhang, Shanshan Wu   +5 more
wiley   +1 more source

THE URBANOLOGISTS COME TO TOWN: Professional Life and Work in the Urban Solutions Industry

International Journal of Urban and Regional Research, EarlyView.
Abstract This article charts the upsurge of an eclectic global community of professionals new to the field of urban policy and governance, animated by playful and celebratory attitudes towards cities and urbanization: the urbanologists. It contributes to debates in critical urban theory and critical ethnographies of technology to problematize ...
Rachel Bok
wiley   +1 more source

Relationship of Sedentary Lifestyle With Hypertension Incidence in Productive Ages (20-59 Years) Among Educators and Educational Staff in Jember, Indonesia

Jurnal Ilmu Kesehatan Masyarakat
Hypertension remained a major global health issue that had not been fully addressed, causing 10.8 million deaths and serving as the leading risk factor for mortality worldwide.
Qaimima Ayuni, Citra Anggun Kinanthi, Irma Prasetyowati   +2 more
doaj   +1 more source

Chronic Venous Disease in Patients With Hidradenitis Suppurativa and Lymphedema: An Overlooked Problem

JEADV Clinical Practice, EarlyView.
Patricia Garbayo‐Salmons, Alejandro Molina‐Leyva, Rafael S. Aguayo‐Ortiz, Eva Vilarrasa   +3 more
wiley   +1 more source

Does Proactivity Affect Insurance Solidarity and Individual Responsibility?

The British Journal of Sociology, EarlyView.
ABSTRACT Over the past 20 years, the insurance industry has been experimenting with technological innovations that deeply affect its business model and social function. This article explores the use of digital technologies to monitor policyholders' behaviour and personalise their insurance coverage.
Alberto Cevolini, Elena Esposito
wiley   +1 more source