Results 51 to 60 of about 83,571 (346)

Identification of Milankovitch sedimentary cycle in Fengcheng Formation, Mahu depression: a case study of well Maye 1

Frontiers in Earth Science
The sedimentary cycle of Fengcheng Formation in Junggar Basin changes rapidly and is difficult to identify. The low classification accuracy of high-frequency fine-grained sedimentary cycles restricts the exploration of unconventional shale oil and gas ...
Ran Wang, Xuan Chen, Qiusheng Chang, Xinmei Zhao   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Slope stability in slightly fissured claystones and marls [PDF]

, 2015
The final publication is available at Springer via http://dx.doi.org/10.1007/s10346-014-0526-5The paper deals with the behavior of some characteristic soft rocks found in the Iberian Peninsula.
Alonso Pérez de Agreda, Eduardo, Pinyol Puigmartí, Núria Mercè   +1 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Lithofacial characteristic and cyclic analysis of the Middle Triassic of the Pronchishchev Range (north of Middle Siberia)

Литосфера, 2017
The object of study is clastic Middle Triassic of the central part of the Pronchishchev Range. The territory of researches is located on the border of Ust’-Anabar and Lena-Olenek facies districts and has poor geological knowledge.
Aleksei Yu. Popov, Evgenii S. Sobolev, Andrei V. Yadrenkin   +2 more
doaj   +2 more sources

Integrated stratigraphy of the Upper Hauterivian to Lower Barremian Agua de la Mula Member of the Agrio Formation, Neuquén Basin, Argentina [PDF]

, 2011
The Upper Hauterivian to Lower Barremian Agua de la Mula Member of the Agrio Formation (Neuquén Basin, Argentina) was studied applying an integrated stratigraphic approach and facies analysis.
Archuby, Fernando, Leanza, Hector Armando, Wilmsen, Markus   +2 more
core  

Modeling eutrophication and oligotrophication of shallow-water marine systems: the importance of sediments under stratified and well-mixed conditions [PDF]

, 2009
A one-dimensional model that couples water-column physics with pelagic and benthic biogeochemistry in a 50-m-deep water column is used to demonstrate the importance of the sediment in the functioning of shallow systems, the eutrophication status of the ...
Middelburg, J.J., Soetaert, K.E.R.
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Spatiotemporal evolution of single sandbodies controlled by allocyclicity and autocyclicity in the shallow-water braided river delta front of an open lacustrine basin

Open Geosciences, 2021
The spatial and temporal evolution of the sandbody architecture of shallow-water deltas in open lacustrine basins is controlled by the classification of allocyclicity and autocyclicity.
Tong Qiang, Jiao Tao, Qi Zhao, Wang Haihong, Liu Yicang, Zhu Yushuang, Liu Hanlin   +6 more
doaj   +1 more source