Results 101 to 110 of about 845,609 (237)
Advanced Science, EarlyView.In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian +13 more
wiley +1 more source
Remembrance and Reconciliation: Understanding the Little Rock Crisis of 1957 video recordings, 1997
, 1997 Collection contains nine videocassette tapes recording the public symposium, "Remembrance and Reconciliation: Understanding the Little Rock Crisis of 1957," held on 1997 September 26-27, at the University of Arkansas at Little Rock. Participants included:
University of Arkansas at Little Rock.
core
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
Advanced Science, EarlyView.This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Boosting Charge Storage in Ferri/Ferrocyanide‐Based Alkaline Redox Flow Batteries
Angewandte Chemie, EarlyView.By modifying the solvation environment, cation engineering through Li+ substitution of traditional K+ or Na+ boosts the alkaline solubility of the ferri/ferrocyanide catholyte redox couple, providing a viable pathway to overcome the long‐standing challenge of energy density limitations for aqueous redox flow batteries (RBFs).
Mahla Sarfaraz Khabbaz +6 more
wiley +2 more sources
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
Angewandte Chemie, EarlyView.Metadynamics simulations drive automated reaction exploration of acid‐catalysed drug degradation, generating a network spanning 1720 species and 2471 elementary steps. QM‐based filtering reduces the network to eight candidate pathways for rigorous DFT refinement and microkinetic modelling.
Julius Seumer +5 more
wiley +2 more sources
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
Advanced Science, EarlyView.A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao +10 more
wiley +1 more source
Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries
Advanced Energy Materials, EarlyView.This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee +3 more
wiley +1 more source
On‐Demand Deconstructable Thermosets Through Cleavable Comonomer and Thermolatent Base Synergy
Angewandte Chemie, EarlyView.Thermosets, valued for their chemical and mechanical properties, resist recycling due to their cross‐linked structure. Weak bonds via comonomers enable degradability, but diffusion limits effectiveness. We incorporate thermolatent bases before polymerization (thermal or 3D‐VAT printing).
Sophia Kouider +15 more
wiley +2 more sources
Advanced Energy Materials, EarlyView.Ni‐rich cathodes in sulfide‐based ASSBs undergo intertwined (electro)chemical and mechanical degradation. Here, a new diagnostic framework is presented to decouple each contribution by partitioning capacity fading into charge and discharge fading.
Jangwhan Seok +12 more
wiley +1 more source