Results 201 to 210 of about 168,805 (300)

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Enhancement of the Plant‐Accessible Phosphate Fraction in Sewage Sludge Ashes by Na+ or K+ Addition Prior to Combustion

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
The addition of Na2CO3 or K2CO3 to sewage sludge prior to combustion leads to the production of ashes containing phosphate in the form of buchwaldite‐like phases (Ca(Na/K)PO4). Compared to conventional sewage sludge mono‐ashes, such Na‐ or K‐ashes show greatly increased P‐solubilities and proved to be potent P‐fertiliser materials in greenhouse ...
Lorenz Bier‐Schorr   +4 more
wiley   +1 more source

Electrode structures of solid–liquid interface‐based triboelectric nanogenerators and their applications

open access: yesDroplet, EarlyView.
In this review, we have summarized the working principles and equivalent circuit diagrams of solid‐liquid interface triboelectric nanogenerators with different electrode structures, as well as the applications of devices with such structures in droplet mechanical energy harvesting and self‐powered sensing of liquid samples, along with their respective ...
Hanyue Liu   +7 more
wiley   +1 more source

Resonance‐induced restoration of rock permeability degraded by heavy components of crude oil

open access: yesDeep Underground Science and Engineering, EarlyView.
Resonance‐induced changes occur in filtration properties of sedimentary rocks in crude paraffin oil flow under acoustic vibrations. Experimental data on (a) pressure drop; (b) permeability; (c) pressure at the rock inlet; and (d) pressure at the rock outlet are presented.
Evgenii Riabokon   +6 more
wiley   +1 more source

Geology and land use as key drivers for hydrogeochemistry in a mining district of the Quadrilátero Ferrífero, Brazil: implications for water management strategies. [PDF]

open access: yesEnviron Geochem Health
Salomão GN   +9 more
europepmc   +1 more source

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