Results 231 to 240 of about 137,466 (363)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

open access: yesAdvanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen   +30 more
wiley   +1 more source

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

open access: yesAdvanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong   +7 more
wiley   +1 more source

Smart Nanogels as Enzyme‐Driven Nanomotors for Navigating Viscous Physiological Barriers

open access: yesAdvanced Functional Materials, EarlyView.
Two families of urease‐powered nanomotors (NMs), with and without a p‐(2‐hydroxyethyl methacrylate) (p‐HEMA) shell, have been successfully prepared. Both types exhibit effective motion in highly viscous synovial fluid media at low urea concentrations (25 mM).
David Esporrín‐Ubieto   +6 more
wiley   +1 more source

High Dynamic Range Thin‐Film Resistive Flow Sensors for Monitoring Diverse Biofluids

open access: yesAdvanced Functional Materials, EarlyView.
Thin‐film resistive flow sensors with thermoresistive and piezoresistive mechanisms are developed for biofluid monitoring. Fabricated using biocompatible materials and laser micromachining, the devices achieve sub‐millimeter dimensions and a broad dynamic range.
Latifah Almulla   +2 more
wiley   +1 more source

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