Results 101 to 110 of about 3,925,714 (336)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

A sedimentation test to measure heat stability of milk protein beverages

Journal of Dairy Science
: A small-scale oil bath immersion-heating system using sealed stainless-steel process tubes was developed that has the flexibility to evaluate a wide range of holding temperatures and times. After heat treatment and rapid cooling, the liquid product was
Drew Hargrove, David M. Barbano, MaryAnne Drake   +2 more
doaj   +1 more source

Bidisperse Magnetic Particles Coated with Gelatin and Graphite Oxide: Magnetorheology, Dispersion Stability, and the Nanoparticle-Enhancing Effect

Nanomaterials, 2018
The magnetorheology and dispersion stability of bidisperse magnetic particles (BMP)-based magnetorheological (MR) fluids were improved by applying a novel functional coating composed of gelatin and graphite oxide (GO) to the surfaces of the micron-sized ...
Yu Fu, Jianjun Yao, Honghao Zhao, Gang Zhao, Zhenshuai Wan, Ying Qiu   +5 more
doaj   +1 more source

Lecture notes on sediment transportation and channel stability [PDF]

, 1961
These notes have been prepared for a series of lectures on sediment transportation and channel stability given by the authors to a group of engineers and geologists of the U. S. Department of Agriculture assembled at Caltech on September 12-16,1960. The
Brooks, Norman H., Kennedy, John F. (John Fisher), Vanoni, Vito A.   +2 more
core   +1 more source

GPU-accelerated simulation of colloidal suspensions with direct hydrodynamic interactions

, 2012
Solvent-mediated hydrodynamic interactions between colloidal particles can significantly alter their dynamics. We discuss the implementation of Stokesian dynamics in leading approximation for streaming processors as provided by the compute unified device
Höfling, Felix, Kopp, Michael
core   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

The Effect of Calcium, Citrate, and Urea on the Stability of Ultra-High Temperature Treated Milk: A Full Factorial Designed Study

Foods, 2019
The composition of raw milk is important for the stability of dairy products with a long shelf-life. Based on known historical changes in raw milk composition, the aim of this study was to get a better understanding of how possible future variations in ...
Maria A. Karlsson, Åse Lundh, Fredrik Innings, Annika Höjer, Malin Wikström, Maud Langton   +5 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

D.3.6 – Sediment Dynamics And Stability

, 2017
The objective of the FAST project is to develop a Copernicus downstream service based on (Sentinel) satellite data and in situ data to assess the function of wetlands in reducing flood risk and erosion. This requires an assessment of the erodibility and stability of foreshores, as well as knowledge on how saltmarshes function and develop, in order to ...
van der Wal, Daphne, Evans, Ben R., Willemsen, Pim W.J.M., Morris, Edward P., Bouma, Tjeerd J.   +4 more
openaire   +2 more sources