Results 31 to 40 of about 2,452,019 (253)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Study on the tribological and rheological properties of magnetorheological fluids based on different base oils

open access: yesMaterials Research Express
Base oil has great influence on the tribological and rheological properties of magnetorheological fluid. In this paper, four types of magnetorheological fluid are prepared respectively by silicone oil, mineral oil, synthetic oil (PAO) and castor oil, and
Long Yu, Fei Chen, Hao-Peng Li
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Application of the UNIFAC Model for the Low-Sulfur Residue Marine Fuel Asphaltenes Solubility Calculation

open access: yesJournal of Marine Science and Engineering, 2022
Since 2020, 0.5% limits on the sulfur content of marine fuels have been in effect worldwide. One way to achieve this value is to mix the residual sulfur and distillate low sulfur components.
Vladimir G. Povarov   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Stability of Cement Grout: Study of Sedimentation Phenomena

open access: yesApplied Rheology, 2002
The grouts are suspensions containing cement used in the technique of prestressing by post-tension. Cement, from its chemical nature, protects the wire ropes (strands) from corrosion.
Gelade Pierre   +3 more
doaj   +1 more source

Experimental study on effects of initial concentration on settling velocity characteristics of turbid surface of South China Sea coral mud

open access: yesYantu gongcheng xuebao, 2018
The coral mud is the calcareous ooze composed of fine-grained coral debris, which is distributed in the form of sandwich by particle sorting. During the formation process of an entire filling site, the sedimentary characteristics of the coral mud will ...
SHEN Yang 1, FENG Zhao-yan 1, LIU Han-long 2,1, WANG Qin-cheng 1, LI An 1
doaj   +1 more source

Effect of concentrated brine on coal slurry stability and sedimentation

open access: yes矿业科学学报, 2020
In order to solve the problem of comprehensive utilization of concentrated brine in coal chemical industry, the flocculating settlement test was carried out by using concentrated brine instead of coagulant in coal chemical industry, and the effect of pH ...
Xu Hongxiang   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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