Results 41 to 50 of about 100,674 (267)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Analysis of the synchronous rise of water level in the Tangshan fault zone

Scientific Reports
Since 2019, a synchronous and abnormal upward trend in water levels has been observed in the Tangshan and Majiagou observation wells, located within the Tangshan fault zone, coinciding with three earthquakes of magnitude 4.0 or higher in the Tangshan ...
Jie Tang, Suxin Zhang, Dong Ma, Yan Wang, Lina Sun, Wenlou Luan   +5 more
doaj   +1 more source

An Integrated Monitoring Approach to the Evaluation of the Environmental Impact of an Inshore Mariculture Plant (Mar Grande of Taranto, Ionian Sea)

Biology, 2022
The results of an ex-ante survey aiming to assess the impact of a fish farm in the Mar Grande of Taranto (southern Italy, Mediterranean Sea) on the surrounding environment are reported.
Adriana Giangrande, Margherita Licciano, Daniele Arduini, Jacopo Borghese, Cataldo Pierri, Roberta Trani, Caterina Longo, Antonella Petrocelli, Patrizia Ricci, Giorgio Alabiso, Rosa Anna Cavallo, Maria Immacolata Acquaviva, Marcella Narracci, Loredana Stabili   +13 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Tool4S: A GUI-based python software tool for seismic station site selection data processing and analysis

SoftwareX
Data quality is the foundation of further research. It’s essential to find a seismic station whose data could be collected without being significantly affected by surrounding noise sources.
Cheng Ding, Chengli Jiao, Shuang Zheng, Zhiyuan Zhao, Xiangdong Feng   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Speciation of Sedimentary Phosphorus in an Urban Wetland: The Case of El Oulfa Pound. Casablanca, Morocco [PDF]

E3S Web of Conferences
Eutrophication remains a major concern for the quality of surface waters worldwide. This phenomenon significantly restricts water usage. The El Oulfa pond, located in Casablanca, is experiencing advanced eutrophication primarily caused by domestic ...
Nachchach Badr, Jounaid Halima, Taoufik Mohammed, Chakri Nihad, Elamrani Btissam, Dialo Wandé   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source