Results 111 to 120 of about 249,220 (266)

Contaminated Aquatic Sediments [PDF]

open access: yesWater Environment Research, 2007
A review of the literature published in 2014 relating to the assessment, evaluation and remediation of contaminated aquatic sediments is presented. The review is divided into the following sections: policy and guidance, methodology, distribution, fate and transport, bioavailability, bioaccumulation, risk, toxicity and remediation.
openaire   +9 more sources

Background levels of heavy metals in surficial sediments of the Gulf of Lions (NW Mediterranean): An approach based on 133Cs normalization and lead isotope measurements [PDF]

open access: yes, 2005
This paper presents an attempt to reach natural background levels of heavy metals in surficial sediments of the Gulf of Lions(NW Mediterranean). To correct for the grain-size effect, normalization procedures based on a clay mineral indicator element are ...
Probst, Jean-Luc   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Mechanisms for accumulation and migration of technetium-99 in saltmarsh sediments

open access: yes, 2000
This thesis describes the development of analytical methods for both the bulk determination of 99Tc, and determination of 99Tc in sequential extracts from sediments.
Wigley, F.
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Dynamics of Trace Metal Interactions with Authigenic Sulfide Minerals in Anoxic Sediments

open access: yes, 1995
pgs. 187-199Sediments are the dominant sink for trace metals of environmental concern in most aquatic environments. It is consequently important to understand the chemical behavior of trace metals in sediments in order to assess their potential impact on
Morse, John W.
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Methane Gas Hydrate Morphology and its Effect on the Stiffness and Damping of some Sediments [PDF]

open access: yes, 2009
Gas hydrates are ice–like compounds found in deep sea sediments and permafrosts. Concise detectionand quantification of natural methane gas hydrate deposits, will allow for a more robust assessmentof gas hydrate as a potential energy resource or natural ...
Rees, Emily V L, Rees, Emily V.L.
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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